Evidence map›Paper›PMID 36773497›Full record

ReviewCurrent opinion in neurobiology2023

Stuck on you: Meninges cellular crosstalk in development.

Christina N Como, Sol Kim, Julie Siegenthaler

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. The meningeal-cerebellar axis: a new perspective on cerebellar development.Cellular and molecular life sciences : CMLS · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christina N ComoDepartment of Pediatrics Section of Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Neuroscience Graduate Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Electronic address: https://twitter.com/ChristinaComo.
Sol KimDepartment of Pediatrics Section of Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Cell Biology, Stem Cells, and Development Graduate Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Julie SiegenthalerDepartment of Pediatrics Section of Developmental Biology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Cell Biology, Stem Cells, and Development Graduate Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Neuroscience Graduate Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; University of Colorado, School of Medicine Department of Pediatrics 12800 East 19th Ave MS-8313 Aurora, CO 80045, USA. Electronic address: julie.siegenthaler@cuanschutz.edu.

Funding

Retinoic Acid in Development of CNS VasculatureR01NS098273 · NINDS · UNIVERSITY OF COLORADO DENVER · PI SIEGENTHALER, JULIE · 2016 to 2025
$3.2M
Development and function the meninges arachnoid barrierR56NS098273 · NINDS · UNIVERSITY OF COLORADO DENVER · PI SIEGENTHALER, JULIE · 2021 to 2021
$440k
Formation and Function of the MeningesR03NS127154 · NINDS · UNIVERSITY OF COLORADO DENVER · PI SIEGENTHALER, JULIE · 2022 to 2023
$156k
NINDS NIH HHS R01 NS098273NINDS NIH HHS R03 NS127154NINDS NIH HHS R56 NS098273
6 · The paper itself

Abstract

The spatial and temporal development of the brain, overlying meninges (fibroblasts, vasculature and immune cells) and calvarium are highly coordinated. In particular, the timing of meningeal fibroblasts into molecularly distinct pia, arachnoid and dura subtypes coincides with key developmental events in the brain and calvarium. Further, the meninges are positioned to influence development of adjacent structures and do so via depositing basement membrane and producing molecular cues to regulate brain and calvarial development. Here, we review the current knowledge of how meninges development aligns with events in the brain and calvarium and meningeal fibroblast "crosstalk" with these structures. We summarize outstanding questions and how the use of non-mammalian models to study the meninges will substantially advance the field of meninges biology.

Indexed as

Dura MaterMeningesArachnoidBrain

Identifiers

PMID36773497
PMCPMC10023464

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.