Trial reportBrain connectivity2023
Stimulation of the Premotor Cortex Enhances Interhemispheric Functional Connectivity in Association with Upper Limb Motor Recovery in Moderate-to-Severe Chronic Stroke.
Open access · greenAbstract readRandomized Controlled Trial
In one paragraph
Trial report in Brain connectivity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 5 pooled it
3.2field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Effects of telerehabilitation monitored home-based therapies on upper extremity function-related outcomes in children and adolescents with unilateral cerebral palsy: A systematic review.Journal of telemedicine and telecare · 2026Pooled it
- Biomarker use in predicting transcranial direct-current stimulation (tDCS) response: a systematic scoping review.Frontiers in psychiatry · 2026Pooled it
- Completion rate and safety of non-invasive brain stimulation for upper limb dysfunction after stroke: a systematic review and network meta-analysis.Frontiers in neurology · 2026Pooled it
- Systematic review: Resting state functional MRI as a biomarker for non-invasive brain stimulation in upper limb recovery post-stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Pooled it
- Does a single session of transcranial direct current stimulation enhance both physical and psychological performance in national- or international-level athletes? A systematic review.Frontiers in physiology · 2024Pooled it
- Repetitive Transcranial Magnetic Stimulation of the Contralesional Dorsal Premotor Cortex for Upper Extremity Motor Improvement in Severe Stroke: A Pilot Randomized Clinical Trial.American journal of physical medicine & rehabilitation · 2026Trial
- Transcranial magnetic stimulation regulates brain functional network dynamics in stroke patients: a randomised controlled trial.Journal of neuroengineering and rehabilitation · 2025Trial
- Transcranial direct current stimulation over the motor and premotor cortex with mirror therapy improves motor control, muscle function, and brain activity in chronic stroke: a double-blind randomized sham-controlled trial.Journal of neuroengineering and rehabilitation · 2025Trial
- Trial
- Transcranial direct current stimulation-induced changes in motor cortical connectivity are associated with motor gains following ischemic stroke.Scientific reports · 2024Trial
- Associations Between Early Functional Brain Network Topology and 6-Month Upper Limb Motor Outcomes in Stroke Patients.Translational stroke research · 2026Article
- Functional Neuroimaging as a Biomarker of Non-Invasive Brain Stimulation in Upper Limb Recovery After Stroke: A Systematic Review and Narrative Discussion.Biomedicines · 2026Review
- Motor Fiber Tract Changes Following iTBS Stimulation in a Basal Ganglia Stroke Patient: A Case Report.Clinical case reports · 2026Article
- Dynamic Interactions Between Hemispheres Reveal a Compensatory Pathway for Motor Recovery in Moderate-to-Severe Subcortical Stroke.Journal of stroke · 2026Article
- Transcranial electrical stimulation (TES) in human motor Optimization: Mechanisms, safety, and emerging applications.Biochemistry and biophysics reports · 2025Review
- Stratification algorithm for repetitive TMS in stroke (START): Results from an exploratory crossover study.Journal of the neurological sciences · 2025Article
- The clinical efficacy and mechanism of gamma frequency electroacupuncture stimulation on the rehabilitation of upper limb motor function in stroke patients: study protocol of a randomized clinical trial.Frontiers in neurology · 2025Article
- Neurostimulation After Stroke.Physical medicine and rehabilitation clinics of North America · 2024Review
- Use of functional magnetic resonance imaging to identify cortical loci for lower limb movements and their efficacy for individuals after stroke.Journal of neuroengineering and rehabilitation · 2024Article
- The stratified effects of repetitive transcranial magnetic stimulation in upper limb motor impairment recovery after stroke: a meta-analysis.Frontiers in neurology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Robert H UngerDepartment of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Mark J LoweImaging Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Erik B BeallImaging Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Francois BethouxCenter for Neurological Restoration, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Stephen E JonesImaging Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Andre G MachadoCenter for Neurological Restoration, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Ela B PlowDepartment of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.
David A CunninghamDepartment of Physical Medicine and Rehabilitation, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.ORCID 0000-0003-2246-1548
Cleveland Clinic · USCleveland Clinic Lerner College of Medicine · USMetroHealth · US
Funding
Neurorehabilitation and Restorative Neuroscience NetworkK12HD093427 · NICHD · GEORGETOWN UNIVERSITY · PI BREGMAN, BARBARA S, DROMERICK, ALEXANDER W · 2017 to 2021
$3.9MContralaterally Controlled FES Combined with Brain Stimulation for Severe Upper limb HemiplegiaR01HD098073 · NICHD · CLEVELAND CLINIC LERNER COM-CWRU · PI PLOW, ELA B · 2019 to 2024
$3.1MCase Western Reserve University StrokeNet University Regional Coordinating CenterU24NS107270 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI SOPHIA SUNDARARAJAN, Ken Uchino · 2018 to 2026
$2.4MBrain Stimulation- aided Stroke Rehabilitation: Neural Mechanisms of RecoveryK01HD069504 · NICHD · CLEVELAND CLINIC LERNER COM-CWRU · PI PLOW, ELA B · 2011 to 2015
$531kNICHD NIH HHS K01 HD069504NICHD NIH HHS K12 HD093427NICHD NIH HHS R01 HD098073NINDS NIH HHS U24 NS107270
Abstract
PubMed holds no abstract for this paper.
Indexed as
Motor CortexStrokeTranscranial Direct Current StimulationBrainHumansMagnetic Resonance ImagingTranscranial Magnetic StimulationUpper Extremityplasticitypremotor cortexresting-state functional connectivity magnetic resonance imagingstroketranscranial direct current stimulation
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.