Evidence map›Paper›PMID 36772733›Full record

ArticleSensors (Basel, Switzerland)2023

Convolution Neural Networks and Self-Attention Learners for Alzheimer Dementia Diagnosis from Brain MRI.

Pierluigi Carcagnì, Marco Leo, Marco Del Coco, Cosimo Distante, Andrea De Salve

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pierluigi CarcagnìInstitute of Applied Sciences and Intelligent Systems 1, National Research Council of Italy, 80078 Pozzuoli, Italy.
Marco LeoInstitute of Applied Sciences and Intelligent Systems 1, National Research Council of Italy, 80078 Pozzuoli, Italy.ORCID 0000-0001-5636-6130
Marco Del CocoInstitute of Applied Sciences and Intelligent Systems 1, National Research Council of Italy, 80078 Pozzuoli, Italy.
Cosimo DistanteInstitute of Applied Sciences and Intelligent Systems 1, National Research Council of Italy, 80078 Pozzuoli, Italy.ORCID 0000-0002-1073-2390
Andrea De SalveInstitute of Applied Sciences and Intelligent Systems 1, National Research Council of Italy, 80078 Pozzuoli, Italy.ORCID 0000-0003-1691-7182

Funding

Smartphone-Based "Burst" Cognitive AssessmentsP01AG003991 · NIA · WASHINGTON UNIVERSITY · PI JOHN MORRIS · 1985 to 2026
$69.5M
The natural history of AB accumulation in preclinical ADP01AG026276 · NIA · WASHINGTON UNIVERSITY · PI MORRIS, JOHN · 2005 to 2025
$49.5M
Research Education ComponentP30AG066444 · NIA · WASHINGTON UNIVERSITY · PI DAVID M. HOLTZMAN · 2020 to 2026
$28.7M
NIA NIH HHS P01 AG003991NIA NIH HHS P01 AG026276NIA NIH HHS P30 AG066444
6 · The paper itself

Abstract

Alzheimer's disease (AD) is the most common form of dementia. Computer-aided diagnosis (CAD) can help in the early detection of associated cognitive impairment. The aim of this work is to improve the automatic detection of dementia in MRI brain data. For this purpose, we used an established pipeline that includes the registration, slicing, and classification steps. The contribution of this research was to investigate for the first time, to our knowledge, three current and promising deep convolutional models (ResNet, DenseNet, and EfficientNet) and two transformer-based architectures (MAE and DeiT) for mapping input images to clinical diagnosis. To allow a fair comparison, the experiments were performed on two publicly available datasets (ADNI and OASIS) using multiple benchmarks obtained by changing the number of slices per subject extracted from the available 3D voxels. The experiments showed that very deep ResNet and DenseNet models performed better than the shallow ResNet and VGG versions tested in the literature. It was also found that transformer architectures, and DeiT in particular, produced the best classification results and were more robust to the noise added by increasing the number of slices. A significant improvement in accuracy (up to 7%) was achieved compared to the leading state-of-the-art approaches, paving the way for the use of CAD approaches in real-world applications.

Indexed as

Alzheimer DiseaseDeep LearningBrainHumansMagnetic Resonance ImagingNeural Networks, Computerassistive technologycomputer-aided diagnosisdeep learningmasked auto-encodersmedical image analysisMRIvision transformers

Identifiers

PMID36772733
PMCPMC9919436

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.