Evidence map›Paper›PMID 36771954›Full record

ArticlePolymers2023

Poly(lactic acid) and Nanocrystalline Cellulose Methacrylated Particles for Preparation of Cryogelated and 3D-Printed Scaffolds for Tissue Engineering.

Mariia Leonovich, Viktor Korzhikov-Vlakh, Antonina Lavrentieva, Iliyana Pepelanova, Evgenia Korzhikova-Vlakh, Tatiana Tennikova

Abstract read
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Role of cellulose and its derivatives for 3D printing of bone tissue scaffolds.Frontiers in bioengineering and biotechnology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mariia LeonovichInstitute of Chemistry, Saint Petersburg State University, Peterhoff, Universitetskii pr. 26, 198504 Saint Petersburg, Russia.ORCID 0000-0002-8274-5158
Viktor Korzhikov-VlakhInstitute of Chemistry, Saint Petersburg State University, Peterhoff, Universitetskii pr. 26, 198504 Saint Petersburg, Russia.ORCID 0000-0002-3509-3978
Antonina LavrentievaInstitute of Technical Chemistry, Gottfried-Wilhelm-Leibniz University of Hannover, 30167 Hannover, Germany.ORCID 0000-0003-0003-5572
Iliyana PepelanovaInstitute of Technical Chemistry, Gottfried-Wilhelm-Leibniz University of Hannover, 30167 Hannover, Germany.
Evgenia Korzhikova-VlakhInstitute of Chemistry, Saint Petersburg State University, Peterhoff, Universitetskii pr. 26, 198504 Saint Petersburg, Russia.ORCID 0000-0002-2530-7709
Tatiana TennikovaInstitute of Chemistry, Saint Petersburg State University, Peterhoff, Universitetskii pr. 26, 198504 Saint Petersburg, Russia.ORCID 0000-0002-9029-2056

Funding

Ministry of Science and Higher Education of the Russian Federation 075-15-2021-637
6 · The paper itself

Abstract

Different parts of bones possess different properties, such as the capacity for remodeling cell content, porosity, and protein composition. For various traumatic or surgical tissue defects, the application of tissue-engineered constructs seems to be a promising strategy. Despite significant research efforts, such constructs are still rarely available in the clinic. One of the reasons is the lack of resorbable materials, whose properties can be adjusted according to the intended tissue or tissue contacts. Here, we present our first results on the development of a toolbox, by which the scaffolds with easily tunable mechanical and biological properties could be prepared. Biodegradable poly(lactic acid) and nanocrystalline cellulose methacrylated particles were obtained, characterized, and used for preparation of three-dimensional scaffolds via cryogelation and 3D printing approaches. The composition of particles-based ink for 3D printing was optimized in order to allow formation of stable materials. Both the modified-particle cytotoxicity and the matrix-supported cell adhesion were evaluated and visualized in order to confirm the perspectives of materials application.

Indexed as

3D printingmethacrylationnanocrystalline celluloseparticlespoly(lactic acid)scaffoldstissue engineering

Identifiers

PMID36771954
PMCPMC9920993

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.