Evidence map›Paper›PMID 36771876›Full record

ReviewPolymers2023

Characterization and Analysis of Chitosan-Gelatin Composite-Based Biomaterial Effectivity as Local Hemostatic Agent: A Systematic Review.

Heri Herliana, Harmas Yazid Yusuf, Avi Laviana, Ganesha Wandawa, Arief Cahyanto

Abstract readReview
In one paragraph

Review in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Heri HerlianaDoctoral Program, Faculty of Dentistry, Universitas Padjadjaran, Bandung 45124, Indonesia.ORCID 0000-0003-3249-7149
Harmas Yazid YusufDepartment of Oral and Maxillo Facial Surgery, Faculty of Dentistry, Universitas Padjadjaran, Bandung 45124, Indonesia.
Avi LavianaDepartment of Orthodontic, Faculty of Dentistry, Universitas Padjadjaran, Bandung 45124, Indonesia.ORCID 0000-0002-3770-9625
Ganesha WandawaThe Indonesian Naval Dental Institute, Jakarta 10210, Indonesia.
Arief CahyantoDepartment of Dental Materials Science and Technology, Faculty of Dentistry, Universitas Padjadjaran, Bandung 45124, Indonesia.ORCID 0000-0003-2222-5895

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chitosan and gelatin were the most widely used natural materials in pharmaceutical and medical fields, especially as local hemostatic agents, independently or as a composite material with the addition of other active substances. Chitosan and gelatin have excellent properties in biocompatibility, biodegradability, non-toxicity and water absorption capacity. The objective of this review was to analyze the characteristics of chitosan-gelatin (CG) composite-based biomaterial and its effectivity as a local hemostatic agent. We used PRISMA guidelines and the PICO framework to compile this review. The findings demonstrated that the CG composite-based biomaterial had excellent physical, chemical, mechanical properties and local hemostatic agent activity by adding other active substances such as oxidized fibers (OF), silica nanoparticles (SiNPs), calcium (Ca) and biphasic calcium phosphate (BCP) or by setting the CG composite proportion ratio.

Indexed as

chitosan-gelatincomposite materialhemostatic agent

Identifiers

PMID36771876
PMCPMC9920696

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.