Evidence map›Paper›PMID 36771497›Full record

ArticleNutrients2023

Lifestyle Intervention in NAFLD: Long-Term Diabetes Incidence in Subjects Treated by Web- and Group-Based Programs.

Maria Letizia Petroni, Lucia Brodosi, Angelo Armandi, Francesca Marchignoli, Elisabetta Bugianesi, Giulio Marchesini

Abstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Practical Lifestyle Management of Nonalcoholic Fatty Liver Disease for Busy Clinicians.Diabetes spectrum : a publication of the American Diabetes Association · 2024
    Article
  9. Lifestyle interventions in nonalcoholic fatty liver disease.Nature reviews. Gastroenterology & hepatology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria Letizia PetroniIRCCS-Azienda Ospedaliero, Universitaria di Bologna, 40138 Bologna, Italy.ORCID 0000-0002-7040-6466
Lucia BrodosiIRCCS-Azienda Ospedaliero, Universitaria di Bologna, 40138 Bologna, Italy.ORCID 0000-0002-7735-7847
Angelo ArmandiDepartment of Medical Sciences, Division of Gastroenterology and Hepatology, A.O. Città della Salute e della Scienza di Torino, University of Turin, 10124 Turin, Italy.ORCID 0000-0002-7245-4445
Francesca MarchignoliIRCCS-Azienda Ospedaliero, Universitaria di Bologna, 40138 Bologna, Italy.ORCID 0000-0002-4862-1274
Elisabetta BugianesiDepartment of Medical Sciences, Division of Gastroenterology and Hepatology, A.O. Città della Salute e della Scienza di Torino, University of Turin, 10124 Turin, Italy.ORCID 0000-0002-0502-4381
Giulio MarchesiniDepartment of Medical and Surgical Sciences, Alma Mater University of Bologna, 40138 Bologna, Italy.ORCID 0000-0003-2407-9860

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBehavioral programs are needed for prevention and treatment of NAFLD and the effectiveness of a web-based intervention (WBI) is similar to a standard group-based intervention (GBI) on liver disease biomarkers.

objectiveWe aimed to test the long-term effectiveness of both programs on diabetes incidence, a common outcome in NAFLD progression.

methods546 NAFLD individuals (212 WBI, 334 GBI) were followed up to 60 months with regular 6- to 12-month hospital visits. The two cohorts differed in several socio-demographic and clinical data. In the course of the years, the average BMI similarly decreased in both cohorts, by 5% or more in 24.4% and by 10% or more in 16.5% of cases available at follow-up. After excluding 183 cases with diabetes at entry, diabetes was newly diagnosed in 48 cases during follow-up (31 (16.6% of cases without diabetes at entry) in the GBI cohort vs. 17 (9.7%) in WBI;

conclusionIn individuals with NAFLD, WBI is as effective as GBI on the pending long-term risk of diabetes, via similar results on weight change.

Indexed as

Diabetes MellitusDiabetes Mellitus, Type 2Non-alcoholic Fatty Liver DiseasePrediabetic StateHumansIncidenceLife Stylebehavior therapydiabetes incidencefatty liverlifestyle interventionweb-based intervention

Identifiers

PMID36771497
PMCPMC9919358

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.