Evidence map›Paper›PMID 36771478›Full record

ArticleNutrients2023

The Association of Serum and Dietary Magnesium with Depressive Symptoms.

Ming-Hui Chou, Yen Kuang Yang, Jung-Der Wang, Chung-Ying Lin, Sheng-Hsiang Lin

Abstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ming-Hui ChouDepartment of Public Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.
Yen Kuang YangDepartment of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.
Jung-Der WangDepartment of Public Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.ORCID 0000-0002-3176-4500
Chung-Ying LinInstitute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.ORCID 0000-0002-2129-4242
Sheng-Hsiang LinDepartment of Public Health, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.ORCID 0000-0002-2925-5352

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression is a leading cause of the global burden of disease and has a multifactorial etiology that includes nutrients. Magnesium status has been associated with depression with inconclusive results. The impact of chronic latent magnesium deficiency (CLMD, 0.75 ≤ serum magnesium < 0.85 mmol/L) on depression has not yet been investigated. We assessed the association between serum magnesium levels/dietary magnesium intake and depressive symptoms by analyzing nationally representative data from Taiwan (Nutrition and Health Survey in Taiwan, NAHSIT). We used the 5-item Brief Symptom Rating Scale to measure depressive symptoms. Subgroup analysis by sex was also performed. Serum magnesium levels had a low correlation with dietary magnesium intake. Higher serum magnesium levels were associated with lower depressive scores and a lower risk of depressive symptoms, but dietary magnesium intake showed no association. Sex differences were found. Compared with subjects with serum magnesium <0.75 mmol/L, those with ≥0.85 mmol/L had lower depressive scores. In conclusion, serum magnesium was inversely associated with depressive symptoms, but dietary magnesium intake was not. Subjects with CLMD showed similar depressive scores and were at a similar risk of depressive symptoms to those with serum magnesium < 0.75 mmol/L. CLMD should be considered while assessing the association between magnesium status and depressive symptoms.

Indexed as

Magnesium DeficiencyMalnutritionDepressionFemaleHealth SurveysHumansMagnesiumMaleNutritional StatusMagnesium5-item Brief Symptom Rating Scale (BSRS-5)chronic latent magnesium deficiency (CLMD)depressiondepressive symptomsdietary magnesium intakeNutrition and Health Survey in Taiwan (NAHSIT)serum magnesium

Identifiers

PMID36771478
PMCPMC9920676

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.