ArticleNutrients2023
Association between Edinburgh Postnatal Depression Scale and Serum Levels of Ketone Bodies and Vitamin D, Thyroid Function, and Iron Metabolism.
Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Systematic Review of the Correlation Between Micronutrient Levels and Perinatal Depression.Nutrients · 2025Pooled it
- Association of iron status indicators with thyroid hormone concentrations during pregnancy: a systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- A U-shaped association between vitamin D and ketone levels in type 2 diabetes: a metabolic state-dependent dual regulation mechanism.Diabetology & metabolic syndrome · 2026Article
- Development and external validation of an explainable XGBoost model with a web-based calculator for risk prediction of postpartum depressive symptoms.Frontiers in psychiatry · 2026Article
- Invisible Links: Associations Between Micronutrient Deficiencies and Postpartum Depression-A Systematic Review.Life (Basel, Switzerland) · 2025Review
- Relationship between dietary protein intake and serum essential free amino acid concentrations in Japanese pregnant women: an observational study.BMC pregnancy and childbirth · 2025Observational
- Relationship Between Vitamin D Deficiency and Postpartum Depression.Journal of personalized medicine · 2025Review
- Postpartum depression risk prediction using explainable machine learning algorithms.Frontiers in medicine · 2025Article
- Causal associations between vitamin D and postpartum depression: A bidirectional mendelian randomization study.Heliyon · 2024Article
- Exploring Depression and Nutritional Covariates Amongst US Adults using Shapely Additive Explanations.Health science reports · 2023Article
- Thyroid Predictors of Postpartum Mood Disorders.Cureus · 2023Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Suicide due to postpartum depression is the most common perinatal-related death and is a social concern in Japan. Nutritional deficiencies during pregnancy may contribute to postpartum depression; therefore, we investigated the relationship between postpartum depression and nutritional status during pregnancy and postpartum. We focused specifically on ketone bodies because they are known to protect brain cells. The relationship between the Edinburgh Postnatal Depression Scale (EPDS) scores and the serum levels of ketone bodies and vitamin D, thyroid function, and iron metabolism was examined. Overall, 126 pregnant women were identified for the study, and 99 were eventually included in the analysis. We defined an EPDS score of ≥9 as being positive for postpartum depression, and serum ketone levels were found to be higher in the group with an EPDS score of ≥9 during the second trimester; however, there were no other significant findings. We may be able to predict postpartum depression from a pregnant woman's serum ketone levels in the second trimester. There was a positive correlation between the EPDS scores at 3 days and 1 month postpartum (r = 0.534,
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