Evidence map›Paper›PMID 36771430›Full record

ArticleNutrients2023

Dietary Impacts on Changes in Diversity and Abundance of the Murine Microbiome during Progression and Treatment of Cancer.

Holly Paden, Nikola Kurbatfinski, Jelmer W Poelstra, Kate Ormiston, Tonya Orchard, Sanja Ilic

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Holly PadenDepartment of Human Sciences, Ohio State University, Columbus, OH 43210, USA.
Nikola KurbatfinskiDepartment of Human Sciences, Ohio State University, Columbus, OH 43210, USA.
Jelmer W PoelstraMolecular and Cellular Imaging Center (MCIC), Ohio State University, Wooster, OH 44691, USA.ORCID 0000-0002-3514-7462
Kate OrmistonDepartment of Human Sciences, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-2513-8180
Tonya OrchardDepartment of Human Sciences, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-7265-7314
Sanja IlicDepartment of Human Sciences, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-3450-2693
The Ohio State University · USImaging Center · US

Funding

Effect of n-3 fatty acids and sugars on chemotherapy-induced cognitive deficitsR01CA189947 · NCI · OHIO STATE UNIVERSITY · PI DEVRIES, ANNE COURTNEY, LUSTBERG, MARYAM B. · 2015 to 2018
$2.2M
NCI NIH HHS R01 CA189947NIH HHS 5R01CA189947
6 · The paper itself

Abstract

The intestinal microbial population is recognized for its impact on cancer treatment outcomes. Little research has reported microbiome changes during cancer progression or the interplay of disease progression, dietary sugar/fat intake, and the microbiome through surgery and chemotherapy. In this study, the murine gut microbiome was used as a model system, and changes in microbiome diversity, richness, and evenness over the progression of the cancer and treatment were analyzed. Mice were categorized into four diet cohorts, combinations of either high or low sucrose and high or low omega-3 fatty acids, and two treatment cohorts, saline vehicle or chemotherapy, for a total of eight groups. Fecal samples were collected at specific timepoints to assess changes due to diet implementation, onset of cancer, lumpectomy, and chemotherapy.

Indexed as

Gastrointestinal MicrobiomeMicrobiotaNeoplasmsAnimalsDietDisease ProgressionFecesMiceVerrucomicrobiaalpha diversitycancerchemotherapydietary compositiondisease progressionmurine microbiomeomega-3sucrose

Identifiers

PMID36771430
PMCPMC9920799
OpenAlexW4318823433

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.