Evidence map›Paper›PMID 36771347›Full record

ReviewNutrients2023

New Advances in Metabolic Syndrome, from Prevention to Treatment: The Role of Diet and Food.

Donatella Ambroselli, Fabrizio Masciulli, Enrico Romano, Giuseppina Catanzaro, Zein Mersini Besharat, Maria Chiara Massari, Elisabetta Ferretti, Silvia Migliaccio, Luana Izzo, Alberto Ritieni and 8 more

Abstract readReview
In one paragraph

Review in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
104citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

104 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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44 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Donatella AmbroselliLaboratory of Food Chemistry, Department of Chemistry and Technologies of Drugs, Sapienza University of Rome, 00185 Rome, Italy.
Fabrizio MasciulliLaboratory of Food Chemistry, Department of Chemistry and Technologies of Drugs, Sapienza University of Rome, 00185 Rome, Italy.
Enrico RomanoLaboratory of Food Chemistry, Department of Chemistry and Technologies of Drugs, Sapienza University of Rome, 00185 Rome, Italy.
Giuseppina CatanzaroDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-8427-9691
Zein Mersini BesharatDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0003-0317-9854
Maria Chiara MassariDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Elisabetta FerrettiDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0001-7265-6429
Silvia MigliaccioDepartment of Movement, Human and Health Sciences, Health Sciences Section, University "Foro Italico", 00135 Rome, Italy.ORCID 0000-0002-4563-6630
Luana IzzoDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-8365-9032
Alberto RitieniDepartment of Pharmacy, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-0314-8839
Michela GrossoDepartment of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0003-1664-1657
Caterina FormichiDiabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Francesco DottaDiabetes Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 53100 Siena, Italy.
Francesco FrigerioDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-9502-3314
Eleonora BarbieraDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.
Anna Maria GiustiDepartment of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy.ORCID 0000-0002-5694-3732
Cinzia IngallinaLaboratory of Food Chemistry, Department of Chemistry and Technologies of Drugs, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-4817-7318
Luisa ManninaLaboratory of Food Chemistry, Department of Chemistry and Technologies of Drugs, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-8659-5890

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The definition of metabolic syndrome (MetS) has undergone several changes over the years due to the difficulty in establishing universal criteria for it. Underlying the disorders related to MetS is almost invariably a pro-inflammatory state related to altered glucose metabolism, which could lead to elevated cardiovascular risk. Indeed, the complications closely related to MetS are cardiovascular diseases (CVDs) and type 2 diabetes (T2D). It has been observed that the predisposition to metabolic syndrome is modulated by complex interactions between human microbiota, genetic factors, and diet. This review provides a summary of the last decade of literature related to three principal aspects of MetS: (i) the syndrome's definition and classification, pathophysiology, and treatment approaches; (ii) prediction and diagnosis underlying the biomarkers identified by means of advanced methodologies (NMR, LC/GC-MS, and LC, LC-MS); and (iii) the role of foods and food components in prevention and/or treatment of MetS, demonstrating a possible role of specific foods intake in the development of MetS.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2Metabolic SyndromeDietFoodHumansRisk Factorsbiomarkersdietfoodfood componentsmetabolic syndromemetabolomics

Identifiers

PMID36771347
PMCPMC9921449

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.