Evidence map›Paper›PMID 36771345›Full record

ArticleNutrients2023

Association between the Triglyceride-Glucose Index and Vitamin D Status in Type 2 Diabetes Mellitus.

Qunyan Xiang, Hui Xu, Junkun Zhan, Shuzhen Lu, Shuang Li, Yanjiao Wang, Yi Wang, Jieyu He, Yuqing Ni, Linsen Li and 2 more

Abstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Qunyan XiangDepartment of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha 410011, China.
Hui XuDepartment of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha 410011, China.
Junkun ZhanDepartment of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha 410011, China.
Shuzhen LuDepartment of Nursing, Hunan Normal University School of Medicine, Changsha 410013, China.
Shuang LiDepartment of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha 410011, China.
Yanjiao WangDepartment of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha 410011, China.
Yi WangDepartment of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha 410011, China.
Jieyu HeDepartment of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha 410011, China.ORCID 0000-0002-3806-9260
Yuqing NiDepartment of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha 410011, China.
Linsen LiDepartment of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha 410011, China.
Yiyang LiuDepartment of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha 410011, China.
Youshuo LiuDepartment of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha 410011, China.ORCID 0000-0001-9835-4074

Funding

Fundamental Research Funds for the Central Universities of Central South University 2021zzts0377Hunan Provincial Administration of Traditional Chinese Medicine Project D2022102National Natural Science Foundation of China 82071593, 81974223, and 81770833Scientific Research Program of Hunan Provincial Health Commission D202303107884
6 · The paper itself

Abstract

backgroundVitamin D deficiency (VDD) increases the risk for type 2 diabetes mellitus (T2DM), which might be related to insulin resistance (IR). We aimed to explore the association between the triglyceride-glucose (TyG) index, a reliable indicator of IR, and VDD in patients with T2DM.

methodsThere were 1034 participants with T2DM enrolled in the Second Xiangya Hospital of Central South University. The TyG index was calculated as ln (fasting triglyceride (TG, mg/dL) × fasting blood glucose (mg/dL)/2). VDD was defined as 25-hydroxyvitamin D [25(OH)D] level <50 nmol/L.

resultsCorrelation analysis showed a negative association between the TyG index and 25(OH)D level. After adjustments for clinical and laboratory parameters, it was revealed that when taking the Q1 quartile of TyG index as a reference, an increasing trend of VDD prevalence was presented in the other three groups divided by TyG index quartiles, where the OR (95% CI) was 1.708 (1.132-2.576) for Q2, 2.041 (1.315-3.169) for Q3, and 2.543 (1.520-4.253) for Q4 (all

conclusionsPatients with higher TyG index were more likely to have an increased risk of VDD in T2DM population, which may be related to IR.

Indexed as

Diabetes Mellitus, Type 2Insulin ResistanceVitamin D DeficiencyBiomarkersBlood GlucoseCalcifediolGlucoseHumansRisk FactorsTriglyceridesVitaminsBiomarkersBlood GlucoseCalcifediolGlucoseTriglyceridesVitaminsinsulin resistancetriglyceride-glucose indextype 2 diabetes mellitusvitamin D deficiency

Identifiers

PMID36771345
PMCPMC9919416

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.