Evidence map›Paper›PMID 36771335›Full record

ReviewNutrients2023

The Role of a Colon-in-Continuity in Short Bowel Syndrome.

Astrid Verbiest, Palle Bekker Jeppesen, Francisca Joly, Tim Vanuytsel

Abstract readReview
In one paragraph

Review in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Astrid VerbiestTranslational Research Center for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMetA), University of Leuven, 3000 Leuven, Belgium.ORCID 0000-0002-6130-7132
Palle Bekker JeppesenDepartment of Intestinal Failure and Liver Diseases, Rigshospitalet, Copenhagen University Hospital, 2100 Copenhagen, Denmark.ORCID 0000-0001-9680-6938
Francisca JolyDepartment of Gastroenterology, IBD and Nutritional Support, Centre for Intestinal Failure and Intestinal Stroke Center, Hôpital Beaujon, UMR 1149, INSERM, University of Paris, 92110 Clichy, France.
Tim VanuytselTranslational Research Center for Gastrointestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism (ChroMetA), University of Leuven, 3000 Leuven, Belgium.ORCID 0000-0001-8728-0903

Funding

Flanders Research Foundation (FWO Vlaanderen) 1830517N
6 · The paper itself

Abstract

Short bowel syndrome (SBS) is a rare gastrointestinal condition that is defined as having less than 200 cm of remaining small intestine. SBS results from extensive surgical resection and is associated with a high risk for intestinal failure (IF) with a need for parenteral support (PS). Depending on the region of intestinal resection, three different main anatomy types can be distinguished from each other. In this review, we synthesize the current knowledge on the role of the colon in the setting of SBS-IF with a colon-in-continuity (SBS-IF-CiC), e.g., by enhancing the degree of intestinal adaptation, energy salvage, and the role of the microbiota. In addition, the effect of the disease-modifying treatment with glucagon-like peptide-2 (GLP-2) analogs in SBS-IF-CiC and how it differs from patients without a colon will be discussed. Overall, the findings explained in this review highlight the importance of preservation of the colon in SBS-IF.

Indexed as

Short Bowel SyndromeColonGlucagon-Like Peptide 2HumansIntestinesIntestine, SmallGlucagon-Like Peptide 2colon-in-continuityglucagon-like peptide-2 analogsintestinal adaptationintestinal failureparenteral supportshort bowel syndrome

Identifiers

PMID36771335
PMCPMC9918966

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.