Evidence map›Paper›PMID 36771329›Full record

ArticleNutrients2023

The Role of Diet in Tinnitus Onset: A Hospital-Based Case-Control Study from Italy.

Carlotta Micaela Jarach, Alessandra Lugo, Werner Garavello, Piet A van den Brandt, Anna Odone, Christopher R Cederroth, Cristina Bosetti, Silvano Gallus

Abstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Tinnitus.Nature reviews. Disease primers · 2026
    Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Carlotta Micaela JarachDepartment of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.ORCID 0000-0002-9963-1624
Alessandra LugoDepartment of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.ORCID 0000-0002-4297-6496
Werner GaravelloDepartment of Otorhinolaryngology, School of Medicine and Surgery, University of Milan-Bicocca, 20121 Milan, Italy.
Piet A van den BrandtGROW-School for Oncology and Developmental Biology, Department of Epidemiology, Maastricht University Medical Centre, 6211 Maastricht, The Netherlands.
Anna OdoneSchool of Medicine, University Vita-Salute San Raffaele, 20132 Milan, Italy.ORCID 0000-0002-5657-9774
Christopher R CederrothLaboratory of Experimental Audiology, Department of Physiology and Pharmacology, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0001-7267-5136
Cristina BosettiDepartment of Oncology, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.ORCID 0000-0003-2090-4608
Silvano GallusDepartment of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, 20156 Milan, Italy.ORCID 0000-0002-8967-0400

Funding

European Union 848261European Union GNP-182
6 · The paper itself

Abstract

Knowledge on the role of diet in tinnitus onset is mostly based on few cross-sectional studies. In 2016-2019 we conducted a hospital-based case-control study in northern Italy on 185 incident idiopathic tinnitus cases and 198 controls, providing data on dietary habits through a 37-item food-frequency questionnaire. Odds ratios (OR) for tinnitus risk were derived through unconditional multiple logistic regression models. Moderate-to-high vs. low intake of caffeine (OR, 0.49; 95% confidence interval (CI), 0.24-0.99) and butter (OR, 0.46; 95% CI, 0.23-0.93), and high vs. low intake of poultry (OR, 0.43; 95% CI, 0.23-0.81), prosciutto (OR, 0.44; 95% CI, 0.23-0.85), and legumes (OR, 0.50; 95% CI, 0.28-0.92) were inversely associated with tinnitus onset. Other food items, including cereals, red meat, fish, vegetables, and fruit did not show any statistically significant relationship. The variety of food consumed decreased the risk of tinnitus (OR for at least 20 vs. less than 16 different food items, 0.47; 95% CI, 0.24-0.90). Our findings highlight the importance of diet in tinnitus onset and confirm a potential inverse association of protein-rich food and caffeine on the incidence of tinnitus. Confirmation of our findings in longitudinal studies is necessary before proving any diet recommendations for tinnitus prevention.

Indexed as

TinnitusAnimalsCaffeineCase-Control StudiesCross-Sectional StudiesDietFeeding BehaviorFruitItalyRisk FactorsVegetablesCaffeinecase-control studydietepidemiologylifestylesrisk factorstinnitus

Identifiers

PMID36771329
PMCPMC9920666

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.