Evidence map›Paper›PMID 36771255›Full record

ArticleNutrients2023

Hispidin in the Medicinal Fungus Protects Dopaminergic Neurons from JNK Activation-Regulated Mitochondrial-Dependent Apoptosis in an MPP

Mei-Chou Lai, Wayne-Young Liu, Shorong-Shii Liou, I-Min Liu

Abstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Imidazo[2,1-ACS chemical neuroscience · 2024
    Article
  4. Isolation and Antioxidant Mechanism of Polyphenols fromAntioxidants (Basel, Switzerland) · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mei-Chou LaiDepartment of Pharmacy and Master Program, Collage of Pharmacy and Health Care, Tajen University, Pingtung County 90741, Taiwan.
Wayne-Young LiuDepartment of Urology, Jen-Ai Hospital, Taichung 41265, Taiwan.
Shorong-Shii LiouDepartment of Pharmacy and Master Program, Collage of Pharmacy and Health Care, Tajen University, Pingtung County 90741, Taiwan.
I-Min LiuDepartment of Pharmacy and Master Program, Collage of Pharmacy and Health Care, Tajen University, Pingtung County 90741, Taiwan.

Funding

Ministry of Science and Technology of Taiwan MOST 111-2320-B-127-001
6 · The paper itself

Abstract

Degenerative diseases of the brain include Parkinson's disease (PD), which is associated with moveable signs and is still incurable. Hispidin belongs to polyphenol and originates primarily from the medicinal fungi Inonotus and Phellinus, with distinct biological effects. In the study, MES23.5 cells were induced by 1-methyl-4-phenylpyridinium (MPP

Indexed as

Neuroprotective AgentsParkinson Disease1-Methyl-4-phenylpyridiniumApoptosisCell LineCell Line, TumorDopaminergic NeuronsHumansMitochondriaPyronesReactive Oxygen Species1-Methyl-4-phenylpyridiniumhispidinNeuroprotective AgentsPyronesReactive Oxygen Species1-methyl-4-phenylpyridiniumhispidinmedicinal fungusMS23.5 cellsParkinson’s disease

Identifiers

PMID36771255
PMCPMC9920671

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.