Evidence map›Paper›PMID 36771155›Full record

ReviewMolecules (Basel, Switzerland)2023

Microbial Production of Human Milk Oligosaccharides.

Dileep Sai Kumar Palur, Shannon R Pressley, Shota Atsumi

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Multienzyme Platform for the Synthesis of UDP Sugars and Human Milk Oligosaccharides.Chembiochem : a European journal of chemical biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Dileep Sai Kumar PalurDepartment of Chemistry, University of California, Davis, Davis, CA 95616, USA.
Shannon R PressleyDepartment of Chemistry, University of California, Davis, Davis, CA 95616, USA.
Shota AtsumiDepartment of Chemistry, University of California, Davis, Davis, CA 95616, USA.ORCID 0000-0002-5782-4196
University of California, Davis · US

Funding

Microbial production of fucosylated human milk oligosaccharidesR01GM145842 · NIGMS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ATSUMI, SHOTA · 2022 to 2025
$1.2M
NIGMS NIH HHS R01 GM145842NIH HHS GM145842
6 · The paper itself

Abstract

Human milk oligosaccharides (HMOs) are complex nonnutritive sugars present in human milk. These sugars possess prebiotic, immunomodulatory, and antagonistic properties towards pathogens and therefore are important for the health and well-being of newborn babies. Lower prevalence of breastfeeding around the globe, rising popularity of nutraceuticals, and low availability of HMOs have inspired efforts to develop economically feasible and efficient industrial-scale production platforms for HMOs. Recent progress in synthetic biology and metabolic engineering tools has enabled microbial systems to be a production system of HMOs. In this regard, the model organism

Indexed as

Milk, HumanOligosaccharidesBreast FeedingFemaleHumansInfantInfant, NewbornMetabolic EngineeringSugarsOligosaccharidesSugarshuman milk oligosaccharidesmetabolic engineeringsynthetic biology

Identifiers

PMID36771155
PMCPMC9921495
OpenAlexW4319082078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.