Evidence map›Paper›PMID 36771147›Full record

ArticleMolecules (Basel, Switzerland)2023

Novel Indole-Containing Hybrids Derived from Millepachine: Synthesis, Biological Evaluation and Antitumor Mechanism Study.

Baoxia Liang, Qing Zou, Lintao Yu, Yali Wang, Jun Yan, Baiqi Huang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Baoxia LiangThe School of Food Science and Biology, Guangdong Polytechnic of Science and Trade, Guangzhou 510430, China.ORCID 0000-0002-8590-0643
Qing ZouThe School of Food Science and Biology, Guangdong Polytechnic of Science and Trade, Guangzhou 510430, China.
Lintao YuSecond Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Yali WangBGI Infection Pharmaceutical Technology, BGI-Shenzhen, Shenzhen 518083, China.
Jun YanSecond Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510120, China.ORCID 0000-0003-1552-8003
Baiqi HuangThe School of Food Science and Biology, Guangdong Polytechnic of Science and Trade, Guangzhou 510430, China.

Funding

National Natural Science Foundation of China 21907017
6 · The paper itself

Abstract

Millepachine, a bioactive natural product isolated from the seeds of Millettia pachycarpa, is reported to display potential antitumor activity. In this study, novel indole-containing hybrids derived from millepachine were designed, synthesized and evaluated for their antitumor activities. Among all the compounds, compound

Indexed as

Antineoplastic AgentsChalconesApoptosisCell Line, TumorCell ProliferationDrug Screening Assays, AntitumorHumansIndolesStructure-Activity RelationshipTubulinTubulin ModulatorsAntineoplastic AgentsChalconesIndolesmillepachineTubulinTubulin Modulatorsantitumormillepachinetubulin polymerization inhibitors

Identifiers

PMID36771147
PMCPMC9921564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.