ArticleMolecules (Basel, Switzerland)2023
Toxicity of the 3,4-Methylenedioxymethamphetamine and Its Enantiomers to
Ana Rita Costa, Virgínia M F Gonçalves, Bruno B Castro, João Soares Carrola, Ivan Langa, Ariana Pereira, Ana Rita Carvalho, Maria Elizabeth Tiritan, Cláudia Ribeiro
Abstract read
In one paragraphArticle in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from itWhat it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
9 authors.
Ana Rita CostaTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, IUCS-CESPU, CRL, 4585-116 Gandra, Portugal.
Virgínia M F GonçalvesTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, IUCS-CESPU, CRL, 4585-116 Gandra, Portugal.ORCID 0000-0002-9151-516X Bruno B CastroCBMA (Centre of Molecular and Environmental Biology), Department of Biology, University of Minho, 4710-057 Braga, Portugal.ORCID 0000-0002-7130-6061 João Soares CarrolaDepartment of Biology and Environment, University of Trás-os-Montes and Alto Douro, Quinta de Prados, 5000-801 Vila Real, Portugal.
Ivan LangaTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, IUCS-CESPU, CRL, 4585-116 Gandra, Portugal.ORCID 0000-0002-6164-1122 Ariana PereiraTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, IUCS-CESPU, CRL, 4585-116 Gandra, Portugal.
Ana Rita CarvalhoTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, IUCS-CESPU, CRL, 4585-116 Gandra, Portugal.
Maria Elizabeth TiritanTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, IUCS-CESPU, CRL, 4585-116 Gandra, Portugal.ORCID 0000-0003-3320-730X Cláudia RibeiroTOXRUN-Toxicology Research Unit, University Institute of Health Sciences, IUCS-CESPU, CRL, 4585-116 Gandra, Portugal.ORCID 0000-0001-7245-4552 Funding
Fundação para a Ciência e Tecnologia PTDC/CTA-AMB/6686/2020Fundação para a Ciência e Tecnologia UIDB/04423/2020 and UIDP/04423/2020 (Group of Natural Products and Medicinal Chemistry-CIIMAR).
6 · The paper itselfAbstract
MDMA (3,4-methylenedioxymethamphetamine) is a chiral psychoactive recreational drug sold in illicit markets as racemate. Studies on the impact of MDMA on aquatic organisms are scarce. While enantioselectivity in toxicity in animals and humans has been reported, none is reported on aquatic organisms. This study aimed to investigate the ecotoxicological effects of MDMA and its enantiomers in
Indexed as
DaphniaN-Methyl-3,4-methylenedioxyamphetamineAcetylcholinesteraseAnimalsChromatographyHumansStereoisomerismAcetylcholinesteraseN-Methyl-3,4-methylenedioxyamphetamineaquatic organismschiralityecotoxicityenantioselectivitypsychoactive drugs
Identifiers
PMID36771119
PMCPMC9920394
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