ArticleMolecules (Basel, Switzerland)2023
3D Printing of pH Indicator Auxetic Hydrogel Skin Wound Dressing.
Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Next-generation epidermal patches: Bridging 3D and multidimensional printing for biomedical and personal care innovations.Bioactive materials · 2026Review
- Vat Photopolymerization-Fabricated Theranostic Hydrogels for Smart Wound Management.Gels (Basel, Switzerland) · 2026Article
- Wearable Sensors Fabricated by 3D-Printed Composite Hydrogel with 2D Fillers.Small methods · 2026Review
- Advancements and Prospects of pH-Responsive Hydrogels in Biomedicine.Gels (Basel, Switzerland) · 2025Review
- Dual-crosslinked zwitterionic hydrogel: a facile platform of wearable colorimetric urea sensors.Mikrochimica acta · 2025Article
- 3D-printed and In-situ prepared hydrogel anti-bacterial wound patch with silver nanoparticle embedded matrix.Heliyon · 2025Article
- Digital light processing printing of non-modified protein-only compositions.Materials today. Bio · 2025Article
- Auxetic Biomedical Metamaterials for Orthopedic Surgery Applications: A Comprehensive Review.Orthopaedic surgery · 2024Review
- Recent Developments in 3D-(Bio)printed Hydrogels as Wound Dressings.Gels (Basel, Switzerland) · 2024Review
- The emerging progress on wound dressings and their application in clinic wound management.Heliyon · 2023Review
- Development and Prospective Applications of 3D Membranes as a Sensor for Monitoring and Inducing Tissue Regeneration.Membranes · 2023Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The benefits of enclosing pH sensors into wound dressings include treatment monitoring of wounded skin and early detection of developing chronic conditions, especially for diabetic patients. A 3D printed re-entrant auxetic hydrogel wound dressing, doped with pH indicator phenol red dye, was developed and characterized. The re-entrant auxetic design allows wound dressing adhesion to complex body parts, such as joints on arms and legs. Tensile tests revealed a yield strength of 140 kPa and Young's modulus of 78 MPa. In addition, the 3D-printed hydrogel has a swelling capacity of up to 14%, limited weight loss to 3% in six days, and porosity of near 1.2%. A reasonable pH response resembling human skin pH (4-10) was obtained and characterized. The integration of color-changing pH indicators allows patients to monitor the wound's healing process using a smartphone. In addition to the above, the mechanical properties and their dependence on post-processing were studied. The results show that the resin composition and the use of post-treatments significantly affect the quality and durability of the wound dressings. Finally, a poly (acrylic acid) (PAA) and water-based adhesive was developed and used to demonstrate the performance of the auxetic wound dressing when attached to moving body joints.
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