Acid-Triggered Switchable Near-Infrared/Shortwave Infrared Absorption and Emission of Indolizine-BODIPY Dyes.

Matthew A Saucier, Cameron Smith, Nicholas A Kruse, Nathan I Hammer, Jared H Delcamp

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

NRF2 Activation by Nitrogen Heterocycles: A Review.Molecules (Basel, Switzerland) · 2023
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matthew A SaucierDepartment of Chemistry and Biochemistry, University of Mississippi, University, MI 38677, USA.ORCID 0000-0002-2565-0806

Cameron SmithDepartment of Chemistry and Biochemistry, University of Mississippi, University, MI 38677, USA.

Nicholas A KruseDepartment of Chemistry and Biochemistry, University of Mississippi, University, MI 38677, USA.

Nathan I HammerDepartment of Chemistry and Biochemistry, University of Mississippi, University, MI 38677, USA.ORCID 0000-0002-6221-2709

Jared H DelcampDepartment of Chemistry and Biochemistry, University of Mississippi, University, MI 38677, USA.ORCID 0000-0001-5313-4078

Funding

National Science Foundation 1757220

6 · The paper itself

Abstract

Fluorescent organic dyes that absorb and emit in the near-infrared (NIR, 700-1000 nm) and shortwave infrared (SWIR, 1000-1700 nm) regions have the potential to produce noninvasive high-contrast biological images and videos. BODIPY dyes are well known for their high quantum yields in the visible energy region. To tune these chromophores to the NIR region, fused nitrogen-based heterocyclic indolizine donors were added to a BODIPY scaffold. The indolizine BODIPY dyes were synthesized via microwave-assisted Knoevenagel condensation with indolizine aldehydes. The non-protonated dyes showed NIR absorption and emission at longer wavelengths than an aniline benchmark. Protonation of the dyes produced a dramatic 0.35 eV bathochromic shift (230 nm shift from 797 nm to 1027 nm) to give a SWIR absorption and emission (λ

Indexed as

BODIPYfluorescence imaging agentsindolizinenear-infrared (NIR) emissionshortwave infrared (SWIR) emission

Identifiers

PMID36770954

DOI10.3390/molecules28031287

PMCPMC9919721

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.