Evidence map›Paper›PMID 36770908›Full record

ReviewMolecules (Basel, Switzerland)2023

Advances in the Study of Probiotics for Immunomodulation and Intervention in Food Allergy.

Yan-Yan Huang, Yan-Tong Liang, Jia-Min Wu, Wei-Tong Wu, Xin-Tong Liu, Ting-Ting Ye, Xiao-Rong Chen, Xin-An Zeng, Muhammad Faisal Manzoor, Lang-Hong Wang

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Next-Generation Probiotics in Allergy Therapy: Scientific Evidence and Clinical Applications.Anti-inflammatory & anti-allergy agents in medicinal chemistry · 2026
    Review
  5. Biotherapeutic Potential of Probiotic YeastIndian journal of microbiology · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Synergistic Synbiotic-ContainingFoods (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yan-Yan HuangCollege of Food Science and Engineering, Foshan University, Foshan 528225, China.
Yan-Tong LiangCollege of Food Science and Engineering, Foshan University, Foshan 528225, China.
Jia-Min WuCollege of Food Science and Engineering, Foshan University, Foshan 528225, China.
Wei-Tong WuCollege of Food Science and Engineering, Foshan University, Foshan 528225, China.
Xin-Tong LiuCollege of Food Science and Engineering, Foshan University, Foshan 528225, China.
Ting-Ting YeCollege of Food Science and Engineering, Foshan University, Foshan 528225, China.
Xiao-Rong ChenCollege of Food Science and Engineering, Foshan University, Foshan 528225, China.
Xin-An ZengCollege of Food Science and Engineering, Foshan University, Foshan 528225, China.
Muhammad Faisal ManzoorCollege of Food Science and Engineering, Foshan University, Foshan 528225, China.ORCID 0000-0002-3705-0277
Lang-Hong WangCollege of Food Science and Engineering, Foshan University, Foshan 528225, China.

Funding

Key Laboratory Project of Guangdong Province 2022B1212010015
6 · The paper itself

Abstract

Food allergies are a serious food safety and public health issue. Soybean, dairy, aquatic, poultry, and nut products are common allergens inducing allergic reactions and adverse symptoms such as atopic dermatitis, allergic eczema, allergic asthma, and allergic rhinitis. Probiotics are assumed as an essential ingredient in maintaining intestinal microorganisms' composition. They have unique physiological roles and therapeutic effects in maintaining the mucosal barrier, immune function, and gastrointestinal tract, inhibiting the invasion of pathogenic bacteria, and preventing diarrhea and food allergies. Multiple pieces of evidence reveal a significant disruptive effect of probiotics on food allergy pathology and progression mechanisms. Thus, this review describes the allergenic proteins as an entry point and briefly describes the application of probiotics in allergenic foods. Then, the role of probiotics in preventing and curing allergic diseases by regulating human immunity through intestinal flora and intestinal barrier, modulating host immune active cells, and improving host amino acid metabolism are described in detail. The anti-allergic role of probiotics in the function and metabolism of the gastrointestinal tract has been comprehensively explored to furnish insights for relieving food allergy symptoms and preventing food allergy.

Indexed as

Dermatitis, AtopicFood HypersensitivityProbioticsAllergensHumansImmunityImmunomodulationAllergensfood allergyimmunityintestinal floraprobiotics

Identifiers

PMID36770908
PMCPMC9919562

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.