Evidence map›Paper›PMID 36770816›Full record

ReviewMolecules (Basel, Switzerland)2023

Porphyrin Macrocycles: General Properties and Theranostic Potential.

Rica Boscencu, Natalia Radulea, Gina Manda, Isabel Ferreira Machado, Radu Petre Socoteanu, Dumitru Lupuliasa, Andreea Mihaela Burloiu, Dragos Paul Mihai, Luis Filipe Vieira Ferreira

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. First evidence of photoinactivation of rapidly growing mycobacteria by tetra-cationic porphyrins with peripheral cisplatin.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Porphyrin-Based Compounds: Synthesis and Application.Molecules (Basel, Switzerland) · 2023
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rica BoscencuFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia, 020956 Bucharest, Romania.
Natalia RaduleaFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia, 020956 Bucharest, Romania.
Gina Manda"Victor Babeş" National Institute of Pathology, 050096 Bucharest, Romania.ORCID 0000-0002-9706-1883
Isabel Ferreira MachadoPolytechnic Institute of Portalegre, 7300-110 Portalegre, Portugal.ORCID 0000-0001-7527-9489
Radu Petre Socoteanu"Ilie Murgulescu" Institute of Physical Chemistry, Romanian Academy, 060021 Bucharest, Romania.
Dumitru LupuliasaFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia, 020956 Bucharest, Romania.
Andreea Mihaela BurloiuFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia, 020956 Bucharest, Romania.
Dragos Paul MihaiFaculty of Pharmacy, "Carol Davila" University of Medicine and Pharmacy, 6 Traian Vuia, 020956 Bucharest, Romania.
Luis Filipe Vieira FerreiraBSIRG-Biospectroscopy and Interfaces Research Group, iBB-Institute for Bioengineering and Biosciences, Instituto Superior Técnico and Associate Laboratory i4HB-Institute for Health and Bioeconomy at Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisboa, Portugal.ORCID 0000-0002-1903-5815

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite specialists' efforts to find the best solutions for cancer diagnosis and therapy, this pathology remains the biggest health threat in the world. Global statistics concerning deaths associated with cancer are alarming; therefore, it is necessary to intensify interdisciplinary research in order to identify efficient strategies for cancer diagnosis and therapy, by using new molecules with optimal therapeutic potential and minimal adverse effects. This review focuses on studies of porphyrin macrocycles with regard to their structural and spectral profiles relevant to their applicability in efficient cancer diagnosis and therapy. Furthermore, we present a critical overview of the main commercial formulations, followed by short descriptions of some strategies approached in the development of third-generation photosensitizers.

Indexed as

NeoplasmsPhotochemotherapyPorphyrinsHumansPhotosensitizing AgentsPrecision MedicinePhotosensitizing AgentsPorphyrinsphotodynamic therapyporphyrin macrocyclestheranostic agents

Identifiers

PMID36770816
PMCPMC9919320

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.