Evidence map›Paper›PMID 36770692›Full record

ArticleMolecules (Basel, Switzerland)2023

The Quantification of Paclitaxel and Its Two Major Metabolites in Biological Samples by HPLC-MS/MS and Its Application in a Pharmacokinetic and Tumor Distribution Study in Xenograft Nude Mouse.

Haijin Huang, Haolin Huang, Yongbing Sun, Qian Liu

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Haijin HuangSuzhou Medical College, Soochow University, 199 Ren'ai Road, Suzhou Industrial Park, Suzhou 215123, China.
Haolin HuangSchool of Stomatology, Fuzhou Medical University, 9 Donglin Road, Fuzhou 344000, China.
Yongbing SunDivision of Pharmaceutics, Jiangxi University of Traditional Chinese Medicine, 1688 Meiling Road, Nanchang 330004, China.
Qian LiuSuzhou Medical College, Soochow University, 199 Ren'ai Road, Suzhou Industrial Park, Suzhou 215123, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A rapid and sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was developed for the quantification of Paclitaxel (PTX), 6α-hydroxypaclitaxel (6α-OHP), and

Indexed as

NeoplasmsPaclitaxelAnimalsChromatography, High Pressure LiquidHeterograftsHumansMiceMice, NudeReproducibility of ResultsTandem Mass SpectrometryTaxoids6-hydroxytaxolPaclitaxelTaxoids6α-hydroxypaclitaxelHPLC–MS/MSp-3′-hydroxypaclitaxelPaclitaxelpharmacokinetics and tissue distributionsolid-phase extraction

Identifiers

PMID36770692
PMCPMC9919154

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.