Evidence map›Paper›PMID 36770624›Full record

ArticleMolecules (Basel, Switzerland)2023

In Vitro, In Vivo, and In Silico Analyses of Molecular Anti-Pigmentation Mechanisms of Selected Thai Rejuvenating Remedy and Bioactive Metabolites.

Sukanya Dej-Adisai, Nitinant Koyphokaisawan, Chatchai Wattanapiromsakul, Wanlapa Nuankaew, Tong Ho Kang, Thanet Pitakbut

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Enhanced Whitening Effect of the Formulations via Inhibition of Tyrosinase Activity by Combination of 4-n-Butylresorcinol, Licochalcone A and Glabridin at an Optimal Ratio.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sukanya Dej-AdisaiDepartment of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai 90112, Songkhla, Thailand.ORCID 0000-0002-8354-3080
Nitinant KoyphokaisawanDepartment of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai 90112, Songkhla, Thailand.
Chatchai WattanapiromsakulDepartment of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai 90112, Songkhla, Thailand.
Wanlapa NuankaewDepartment of Oriental Medicinal Biotechnology, Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin-si 17104, Gyeonggi-do, Republic of Korea.ORCID 0000-0001-5267-6203
Tong Ho KangDepartment of Oriental Medicinal Biotechnology, Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin-si 17104, Gyeonggi-do, Republic of Korea.ORCID 0000-0002-4161-6798
Thanet PitakbutPharmaceutical Biology, Department of Biology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91058 Erlangen, Germany.ORCID 0000-0002-1159-3361

Funding

This research was funded by grant No. PHA6404130S from the Faculty of Pharmaceutical Sciences, Prince of Songkla University, the Discipline of Excellence in Pharmacy and the Faculty of Phar-maceutical Sciences Dissertation Funding for Thesis through the F PHA6404130S
6 · The paper itself

Abstract

Thai rejuvenating remedies are mixed herbal formulas promoting longevity. Due to the complexity, the biological activities of these remedies are minimal. Therefore, in this study, the authors evaluated the anti-pigmentation effect at the molecular level of the selected Thai rejuvenating remedy to fulfill the knowledge gap. First, the authors found that the selected remedy showed promising activity against the tyrosinase enzyme with an IC

Indexed as

Enzyme InhibitorsMonophenol MonooxygenaseAnimalsCinnamatesIsoflavonesMelaninsMolecular Docking SimulationPhenolsZebrafishCinnamatesEnzyme Inhibitorsethyl 4-methoxycinnamateglabridinIsoflavonesMelaninsMonophenol MonooxygenasePhenolsethyl p-methoxycinnamateglabridinMC1R inhibitionmolecular anti-pigmentation mechanismsmolecular dockingplant-derived tyrosinase inhibitorThai rejuvenating remedytyrosinase inhibition

Identifiers

PMID36770624
PMCPMC9920523

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.