Evidence map›Paper›PMID 36770612›Full record

ArticleMolecules (Basel, Switzerland)2023

Synergistic Inhibiting Effect of Phytochemicals in

Yin Xiong, Hye Kyong Kim, Övgü Çelikler Özer, Bert van Duijn, Henrie A A J Korthout, Lihong Zi, Ang Cai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Plant Extracts as Skin Care and Therapeutic Agents.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yin XiongFytagoras B.V., Sylviusweg 72, 2333 BE Leiden, The Netherlands.ORCID 0000-0001-6540-8267
Hye Kyong KimFytagoras B.V., Sylviusweg 72, 2333 BE Leiden, The Netherlands.
Övgü Çelikler ÖzerFytagoras B.V., Sylviusweg 72, 2333 BE Leiden, The Netherlands.ORCID 0000-0002-6369-3364
Bert van DuijnFytagoras B.V., Sylviusweg 72, 2333 BE Leiden, The Netherlands.
Henrie A A J KorthoutFytagoras B.V., Sylviusweg 72, 2333 BE Leiden, The Netherlands.
Lihong ZiFaculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650000, China.
Ang CaiDepartment of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA.ORCID 0000-0003-3197-4257

Funding

Key R&D Project of Yunnan Provincial Science and Technology Department 202003AC100013
6 · The paper itself

Abstract

Tyrosinase (TYR) plays a key role in the enzymatic reaction that is responsible for a range of unwanted discoloration effects, such as food browning and skin hyperpigmentation. TYR inhibitors could, therefore, be candidates for skin care products that aim to repair pigmentation problems. In this study, we used a metabolomics approach combined with the isobologram analysis to identify anti-TYR compounds within natural resources, and evaluate their possible synergism with each other.

Indexed as

CatechinRheumGallic AcidMonophenol MonooxygenasePhytochemicalsPlant ExtractsCatechinGallic AcidMonophenol MonooxygenasePhytochemicalsPlant Extractscatechingallic acidisobologram analysismetabolomicsorthogonal partial least square-modellingRheum palmatumsynergistic effecttyrosinase inhibitory activity

Identifiers

PMID36770612
PMCPMC9919157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.