Evidence map›Paper›PMID 36770595›Full record

ReviewMolecules (Basel, Switzerland)2023

Molecularly Imprinted Nanomaterials with Stimuli Responsiveness for Applications in Biomedicine.

Yan Zhang, Qinghe Wang, Xiao Zhao, Yue Ma, Hongbo Zhang, Guoqing Pan

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yan ZhangSchool of Chemistry and Chemical Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.
Qinghe WangInstitute for Advanced Materials, School of Materials Science and Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.
Xiao ZhaoCollege of Life Sciences, Northwest Normal University, Lanzhou 730071, China.
Yue MaSchool of Chemistry and Chemical Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.ORCID 0000-0002-1849-1384
Hongbo ZhangPharmaceutical Sciences Laboratory, Åbo Akademi University, 20520 Turku, Finland.ORCID 0000-0002-1071-4416
Guoqing PanInstitute for Advanced Materials, School of Materials Science and Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.ORCID 0000-0001-5187-796X

Funding

National Key Research and Development Program of China 2019YFA0112000National Natural Science Foundation of China 32222041 and 21875092Natural Science Foundation of Jiangsu Province BK20220059
6 · The paper itself

Abstract

The review aims to summarize recent reports of stimuli-responsive nanomaterials based on molecularly imprinted polymers (MIPs) and discuss their applications in biomedicine. In the past few decades, MIPs have been proven to show widespread applications as new molecular recognition materials. The development of stimuli-responsive nanomaterials has successfully endowed MIPs with not only affinity properties comparable to those of natural antibodies but also the ability to respond to external stimuli (stimuli-responsive MIPs). In this review, we will discuss the synthesis of MIPs, the classification of stimuli-responsive MIP nanomaterials (MIP-NMs), their dynamic mechanisms, and their applications in biomedicine, including bioanalysis and diagnosis, biological imaging, drug delivery, disease intervention, and others. This review mainly focuses on studies of smart MIP-NMs with biomedical perspectives after 2015. We believe that this review will be helpful for the further exploration of stimuli-responsive MIP-NMs and contribute to expanding their practical applications especially in biomedicine in the near future.

Indexed as

Molecular ImprintingNanostructuresDrug Delivery SystemsMolecularly Imprinted PolymersPolymersMolecularly Imprinted PolymersPolymersbiomedical sciencemolecularly imprinted polymersnanomaterialsstimuli responsiveness

Identifiers

PMID36770595
PMCPMC9919331

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.