Evidence map›Paper›PMID 36770512›Full record

ReviewNanomaterials (Basel, Switzerland)2023

Two Hawks with One Arrow: A Review on Bifunctional Scaffolds for Photothermal Therapy and Bone Regeneration.

Yulong Zhang, Xueyu Liu, Chongrui Geng, Hongyu Shen, Qiupeng Zhang, Yuqing Miao, Jingxiang Wu, Ruizhuo Ouyang, Shuang Zhou

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yulong ZhangInstitute of Bismuth and Rhenium Science, University of Shanghai for Science and Technology, Shanghai 200093, China.
Xueyu LiuInstitute of Bismuth and Rhenium Science, University of Shanghai for Science and Technology, Shanghai 200093, China.
Chongrui GengInstitute of Bismuth and Rhenium Science, University of Shanghai for Science and Technology, Shanghai 200093, China.
Hongyu ShenInstitute of Bismuth and Rhenium Science, University of Shanghai for Science and Technology, Shanghai 200093, China.
Qiupeng ZhangInstitute of Bismuth and Rhenium Science, University of Shanghai for Science and Technology, Shanghai 200093, China.
Yuqing MiaoInstitute of Bismuth and Rhenium Science, University of Shanghai for Science and Technology, Shanghai 200093, China.
Jingxiang WuShanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, China.ORCID 0000-0002-2858-9668
Ruizhuo OuyangInstitute of Bismuth and Rhenium Science, University of Shanghai for Science and Technology, Shanghai 200093, China.ORCID 0000-0001-5091-6816
Shuang ZhouCancer Institute, School of Medicine, Tongji University, Shanghai 200092, China.

Funding

Medical-Engineering Interdisciplinary Project of University of Shanghai for Science and Technology 1022310503National Natural Science Foundation of China 82071233Natural Science Foundation of Shanghai 19ZR1434800Scientific research program of Shanghai Science and Technology Commission 21140903200Shanghai Collaborative Innovation Center of Energy Therapy for Tumors, Clinical research project of Shanghai Municipal Health Commission 201940078
6 · The paper itself

Abstract

Despite the significant improvement in the survival rate of cancer patients, the total cure of bone cancer is still a knotty clinical challenge. Traditional surgical resectionof bone tumors is less than satisfactory, which inevitably results in bone defects and the inevitable residual tumor cells. For the purpose of realizing minimal invasiveness and local curative effects, photothermal therapy (PTT) under the irradiation of near-infrared light has made extensive progress in ablating tumors, and various photothermal therapeutic agents (PTAs) for the treatment of bone tumors have thus been reported in the past few years, has and have tended to focus on osteogenic bio-scaffolds modified with PTAs in order to break through the limitation that PTT lacks, osteogenic capacity. These so-called bifunctional scaffolds simultaneously ablate bone tumors and generate new tissues at the bone defects. This review summarizes the recent application progress of various bifunctional scaffolds and puts forward some practical constraints and future perspectives on bifunctional scaffolds for tumor therapy and bone regeneration: two hawks with one arrow.

Indexed as

bifunctional scaffoldsbone regenerationbone tumorPTAsPTT

Identifiers

PMID36770512
PMCPMC9920372

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.