Evidence map›Paper›PMID 36770480›Full record

ArticleNanomaterials (Basel, Switzerland)2023

Toward Smart Biomimetic Apatite-Based Bone Scaffolds with Spatially Controlled Ion Substitutions.

Edoardo Cianflone, Fabien Brouillet, David Grossin, Jérémy Soulié, Claudie Josse, Sanjana Vig, Maria Helena Fernandes, Christophe Tenailleau, Benjamin Duployer, Carole Thouron and 1 more

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biocompatible MgFeCOBioengineering (Basel, Switzerland) · 2023
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Edoardo CianfloneCIRIMAT, Université de Toulouse, CNRS, INP-ENSIACET, 31030 Toulouse, France.
Fabien BrouilletCIRIMAT, Université de Toulouse, CNRS, UT3 Paul Sabatier, 31062 Toulouse, France.ORCID 0000-0002-8860-9069
David GrossinCIRIMAT, Université de Toulouse, CNRS, INP-ENSIACET, 31030 Toulouse, France.ORCID 0000-0002-4320-2919
Jérémy SouliéCIRIMAT, Université de Toulouse, CNRS, INP-ENSIACET, 31030 Toulouse, France.
Claudie JosseCentre de Microcaractérisation Raimond Castaing, Université de Toulouse, UPS, CNRS, INP, INSA, 31400 Toulouse, France.
Sanjana VigFaculdade de Medicina Dentaria, Universidade do Porto, Rua Dr Manuel Pereira da Silva, 4200-393 Porto, Portugal.ORCID 0000-0001-7939-6500
Maria Helena FernandesFaculdade de Medicina Dentaria, Universidade do Porto, Rua Dr Manuel Pereira da Silva, 4200-393 Porto, Portugal.ORCID 0000-0001-9391-9574
Christophe TenailleauCIRIMAT, Université de Toulouse, CNRS, UT3 Paul Sabatier, 31062 Toulouse, France.
Benjamin DuployerCIRIMAT, Université de Toulouse, CNRS, UT3 Paul Sabatier, 31062 Toulouse, France.
Carole ThouronCIRIMAT, Université de Toulouse, CNRS, INP-ENSIACET, 31030 Toulouse, France.
Christophe DrouetCIRIMAT, Université de Toulouse, CNRS, INP-ENSIACET, 31030 Toulouse, France.ORCID 0000-0002-8471-8719

Funding

AIMed project, European Union's Horizon 2020 research and innovation program, Marie Skłodowska-Curie grant agreement 861138
6 · The paper itself

Abstract

Biomimetic apatites exhibit a high reactivity allowing ion substitutions to modulate their in vivo response. We developed a novel approach combining several bioactive ions in a spatially controlled way in view of subsequent releases to address the sequence of events occurring after implantation, including potential microorganisms' colonization. Innovative micron-sized core-shell particles were designed with an external shell enriched with an antibacterial ion and an internal core substituted with a pro-angiogenic or osteogenic ion. After developing the proof of concept, two ions were particularly considered, Ag

Indexed as

antibacterialbiomimetic apatitebone regenerationcontrolled ion substitutionscore-shell particlesfreeze-castingfreeze drying

Identifiers

PMID36770480
PMCPMC9919144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.