Evidence map›Paper›PMID 36770324›Full record

ArticleMaterials (Basel, Switzerland)2023

Green Synthesized sAuNPs as a Potential Delivery Platform for Cytotoxic Alkaloids.

Byron Mubaiwa, Mookho S Lerata, Nicole R S Sibuyi, Mervin Meyer, Toufiek Samaai, John J Bolton, Edith M Antunes, Denzil R Beukes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Synthesis andRSC advances · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Byron MubaiwaSchool of Pharmacy, University of the Western Cape, Robert Sobukwe Road, Bellville 7535, South Africa.
Mookho S LerataSchool of Pharmacy, University of the Western Cape, Robert Sobukwe Road, Bellville 7535, South Africa.
Nicole R S SibuyiDepartment of Science and Innovation/Mintek Nanotechnology Innovation Centre (DST/Mintek NIC), Bio-Labels Node, Department of Biotechnology, University of the Western Cape, Robert Sobukwe Road, Bellville 7535, South Africa.ORCID 0000-0001-7175-5388
Mervin MeyerDepartment of Science and Innovation/Mintek Nanotechnology Innovation Centre (DST/Mintek NIC), Bio-Labels Node, Department of Biotechnology, University of the Western Cape, Robert Sobukwe Road, Bellville 7535, South Africa.ORCID 0000-0002-8296-4860
Toufiek SamaaiDepartment of Environmental Affairs (Oceans and Coasts), Cape Town 8000, South Africa.ORCID 0000-0001-7269-293X
John J BoltonDepartment of Biological Sciences, University of Cape Town, Rondebosch 7701, South Africa.
Edith M AntunesDepartment of Chemistry, University of the Western Cape, Robert Sobukwe Road, Bellville 7535, South Africa.ORCID 0000-0002-7303-0863
Denzil R BeukesSchool of Pharmacy, University of the Western Cape, Robert Sobukwe Road, Bellville 7535, South Africa.ORCID 0000-0002-0223-2660

Funding

National Research Foundation 93474National Research Foundation 93639
6 · The paper itself

Abstract

The use of natural products as chemotherapeutic agents is well established. However, many are associated with undesirable side effects, including high toxicity and instability. Previous reports on the cytotoxic activity of pyrroloiminoquinones isolated from Latrunculid sponges against cancer cell lines revealed extraordinary activity at IC

Indexed as

cytotoxicitygold nanoparticlesLatrunculid spongespyrroloiminoquinonesSargassum incisifoliumTsitsikamma favus

Identifiers

PMID36770324
PMCPMC9920385

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.