Evidence map›Paper›PMID 36769827›Full record

ArticleJournal of clinical medicine2023

Prospective Assessment of Cerebral Microbleeds with Low-Field Magnetic Resonance Imaging (0.55 Tesla MRI).

Thilo Rusche, Hanns-Christian Breit, Michael Bach, Jakob Wasserthal, Julian Gehweiler, Sebastian Manneck, Johanna M Lieb, Gian Marco De Marchis, Marios Psychogios, Peter B Sporns

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Thilo RuscheDepartment of Radiology, Clinic of Radiology & Nuclear Medicine, University Hospital of Basel, University of Basel, 4001 Basel, Switzerland.ORCID 0000-0002-8712-5759
Hanns-Christian BreitDepartment of Radiology, Clinic of Radiology & Nuclear Medicine, University Hospital of Basel, University of Basel, 4001 Basel, Switzerland.
Michael BachDepartment of Radiology, Clinic of Radiology & Nuclear Medicine, University Hospital of Basel, University of Basel, 4001 Basel, Switzerland.
Jakob WasserthalDepartment of Radiology, Clinic of Radiology & Nuclear Medicine, University Hospital of Basel, University of Basel, 4001 Basel, Switzerland.
Julian GehweilerImamed Radiologie Nordwest AG, 4051 Basel, Switzerland.
Sebastian ManneckDepartment of Radiology, Gesundheitszentrum Fricktal, 4310 Rheinfelden, Switzerland.
Johanna M LiebDepartment of Radiology, Clinic of Radiology & Nuclear Medicine, University Hospital of Basel, University of Basel, 4001 Basel, Switzerland.
Gian Marco De MarchisDepartment of Neurology, University Hospital of Basel, University of Basel, 4001 Basel, Switzerland.
Marios PsychogiosDepartment of Radiology, Clinic of Radiology & Nuclear Medicine, University Hospital of Basel, University of Basel, 4001 Basel, Switzerland.
Peter B SpornsDepartment of Radiology, Clinic of Radiology & Nuclear Medicine, University Hospital of Basel, University of Basel, 4001 Basel, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAccurate detection of cerebral microbleeds (CMBs) on susceptibility-weighted (SWI) magnetic resonance imaging (MRI) is crucial for the characterization of many neurological diseases. Low-field MRI offers greater access at lower costs and lower infrastructural requirements, but also reduced susceptibility artifacts. We therefore evaluated the diagnostic performance for the detection of CMBs of a whole-body low-field MRI in a prospective cohort of suspected stroke patients compared to an established 1.5 T MRI.

methodsA prospective scanner comparison was performed including 27 patients, of whom 3 patients were excluded because the time interval was >1 h between acquisition of the 1.5 T and 0.55 T MRI. All SWI sequences were assessed for the presence, number, and localization of CMBs by two neuroradiologists and additionally underwent a Likert rating with respect to image impression, resolution, noise, contrast, and diagnostic quality.

resultsA total of 24 patients with a mean age of 74 years were included (11 female). Both readers detected the same number and localization of microbleeds in all 24 datasets (sensitivity and specificity 100%; interreader reliability ϰ = 1), with CMBs only being observed in 12 patients. Likert ratings of the sequences at both field strengths regarding overall image quality and diagnostic quality did not reveal significant differences between the 0.55 T and 1.5 T sequences (

conclusionLow-field MRI at 0.55 T may have similar accuracy as 1.5 T scanners for the detection of microbleeds and thus may have great potential as a resource-efficient alternative in the near future.

Indexed as

0.55 Tcerebral microbleedslow-field MRIMRIreading studyscanner comparison

Identifiers

PMID36769827
PMCPMC9917536

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.