Evidence map›Paper›PMID 36769739›Full record

ArticleJournal of clinical medicine2023

Laboratory Diagnostic of Acute Kidney Injury and Its Progression: Risk of Underdiagnosis in Female and Elderly Patients.

Thea Sophie Kister, Maria Schmidt, Lara Heuft, Martin Federbusch, Michael Haase, Thorsten Kaiser

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
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  5. Article
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thea Sophie KisterInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics (ILM), University of Leipzig Medical Center, 04103 Leipzig, Germany.
Maria SchmidtInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics (ILM), University of Leipzig Medical Center, 04103 Leipzig, Germany.ORCID 0000-0002-9479-3659
Lara HeuftInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics (ILM), University of Leipzig Medical Center, 04103 Leipzig, Germany.ORCID 0000-0002-9470-1910
Martin FederbuschInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics (ILM), University of Leipzig Medical Center, 04103 Leipzig, Germany.ORCID 0000-0002-1126-5763
Michael HaaseMedical Faculty, Otto-von-Guericke University Magdeburg, 39106 Magdeburg, Germany.
Thorsten KaiserInstitute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics (ILM), University of Leipzig Medical Center, 04103 Leipzig, Germany.

Funding

Saxon State Parliament (RL eHealthSax 2017/18) 100331796
6 · The paper itself

Abstract

Acute kidney injury (AKI) is a common disease, with high morbidity and mortality rates. In this study, we investigated the potential influence of sex and age on laboratory diagnostics and outcomes. It is known that serum creatinine (SCr) has limitations as a laboratory diagnostic parameter for AKI due to its dependence on muscle mass, which may lead to an incorrect or delayed diagnosis for certain patient groups, such as women and the elderly. Overall, 7592 cases with AKI, hospitalized at the University of Leipzig Medical Center (ULMC) between 1st January 2017 and 31st December 2019, were retrospectively analyzed. The diagnosis and staging of AKI were performed according to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines, based on the level and dynamics of SCr. The impact of sex and age was analyzed by the recalculation of a female to male and an old to young SCr using the CKD-EPI equation. In our study cohort progressive AKI occurred in 19.2% of all cases (

Indexed as

acute kidney injuryage and sexCDSSelderlyKDIGOlaboratory diagnosticsserum creatininewomen

Identifiers

PMID36769739
PMCPMC9917506

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.