Evidence map›Paper›PMID 36769716›Full record

ArticleJournal of clinical medicine2023

Prevalence and Clinical Characteristics of Patients with Torsades de Pointes Complicating Acquired Atrioventricular Block.

Sok-Sithikun Bun, Nathan Heme, Florian Asarisi, Fabien Squara, Didier Scarlatti, Pamela Moceri, Emile Ferrari

Abstract read
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Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sok-Sithikun BunFaculty of Medicine, Pasteur University Hospital, 06000 Nice, France.ORCID 0000-0003-3016-9192
Nathan HemeFaculty of Medicine, Pasteur University Hospital, 06000 Nice, France.ORCID 0000-0001-8933-5226
Florian AsarisiFaculty of Medicine, Pasteur University Hospital, 06000 Nice, France.
Fabien SquaraFaculty of Medicine, Pasteur University Hospital, 06000 Nice, France.
Didier ScarlattiFaculty of Medicine, Pasteur University Hospital, 06000 Nice, France.
Pamela MoceriFaculty of Medicine, Pasteur University Hospital, 06000 Nice, France.
Emile FerrariFaculty of Medicine, Pasteur University Hospital, 06000 Nice, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFemale gender, degree of QT prolongation, and genetic susceptibility are known risk factors for developing torsades de pointes (TdP) during high-grade atrioventricular block (HG-AVB). Our objective was to analyze the prevalence and clinical characteristics of patients presenting with TdP and AVB (TdP [+]) in comparison with non-TdP patients with AVB (TdP [-]).

methodsAll the ECGs from patients prospectively admitted for AVB (2 to 1, HG, and complete) at the University Hospital of Nice were analyzed. Automated corrected QT (QTc), manual measurements of QT and JT intervals, and Tpeak-to-end were performed at the time of the most severe bradycardia.

resultsFrom September 2020 to November 2021, 100 patients were admitted for HG-AVB. Among them, 17 patients with TdP were identified (8 men; 81 ± 10 years). No differences could be identified concerning automated QTc, manual QTc (Bazett correction), baseline QRS width, or mean left ventricular ejection fraction between the two groups. Potassium serum level on admission and mean number of QT-prolonging drugs per patient were not significantly different between the two groups, respectively: 4.34 ± 0.5 mmol/L in TdP [+] versus 4.52 ± 0.6 mmol/L (

conclusionsThe incidence of TdP complicating acquired AVB was 17%. Longer QTc

Indexed as

atrioventricular blockQT intervaltorsades de pointes

Identifiers

PMID36769716
PMCPMC9917754

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