Evidence map›Paper›PMID 36769705›Full record

ArticleJournal of clinical medicine2023

Quality of Life in COVID-Related ARDS Patients One Year after Intensive Care Discharge (Odissea Study): A Multicenter Observational Study.

Cristian Deana, Luigi Vetrugno, Andrea Cortegiani, Silvia Mongodi, Giulia Salve, Matteo Mangiagalli, Annalisa Boscolo, Tommaso Pettenuzzo, Sara Miori, Andrea Sanna and 25 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Cristian DeanaDepartment of Anesthesia and Intensive Care, Health Integrated Agency of Friuli Centrale, 33100 Udine, Italy.ORCID 0000-0002-1626-3177
Luigi VetrugnoDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0003-3745-8368
Andrea CortegianiDepartment of Surgical, Oncological and Oral Science (DiChirOnS), University of Palermo, 90127 Palermo, Italy.ORCID 0000-0003-1416-9993
Silvia MongodiAnesthesia and Intensive Care, Fondazione IRCCS Policlinico S. Matteo, 27100 Pavia, Italy.ORCID 0000-0002-1987-8599
Giulia SalveAnesthesia and Intensive Care, Fondazione IRCCS Policlinico S. Matteo, 27100 Pavia, Italy.
Matteo MangiagalliUnit of Anesthesia and Intensive Care, Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia, 27100 Pavia, Italy.
Annalisa BoscoloInstitute of Anaesthesia and Intensive Care, Padua University Hospital, 35128 Padua, Italy.
Tommaso PettenuzzoInstitute of Anaesthesia and Intensive Care, Padua University Hospital, 35128 Padua, Italy.ORCID 0000-0002-6745-8919
Sara MioriAnesthesia and Intensive Care 1, Santa Chiara Hospital, 38122 Trento, Italy.
Andrea SannaAnesthesia and Intensive Care 1, Santa Chiara Hospital, 38122 Trento, Italy.ORCID 0000-0002-5577-5781
Sergio LassolaAnesthesia and Intensive Care 1, Santa Chiara Hospital, 38122 Trento, Italy.
Sandra MagnoniAnesthesia and Intensive Care 1, Santa Chiara Hospital, 38122 Trento, Italy.ORCID 0000-0002-1723-0844
Elena FerrariIntensive Care Unit, University Hospital of Modena, University of Modena Reggio Emilia, 41124 Modena, Italy.
Emanuela BiagioniIntensive Care Unit, University Hospital of Modena, University of Modena Reggio Emilia, 41124 Modena, Italy.
Flavio BassiDepartment of Anesthesia and Intensive Care, Health Integrated Agency of Friuli Centrale, 33100 Udine, Italy.
Nadia CastaldoPulmonology Unit, Health Integrated Agency of Friuli Centrale, Academic Hospital of Udine, 33100 Udine, Italy.ORCID 0000-0003-4660-0450
Alberto FantinPulmonology Unit, Health Integrated Agency of Friuli Centrale, Academic Hospital of Udine, 33100 Udine, Italy.ORCID 0000-0002-5707-775X
Federico LonghiniAnesthesia and Intensive Care Unit, Department of Medical and Surgical Sciences, University Hospital Mater, Domini, Magna Graecia University, 88100 Catanzaro, Italy.ORCID 0000-0002-6970-7202
Francesco CorradiDepartment of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0002-5588-2608
Francesco ForforiDepartment of Surgical, Medical and Molecular Pathology and Critical Care Medicine, University of Pisa, 56126 Pisa, Italy.
Gianmaria CammarotaDepartment of Medicine and Surgery, University of Perugia, 06121 Perugia, Italy.
Edoardo De RobertisDepartment of Medicine and Surgery, University of Perugia, 06121 Perugia, Italy.ORCID 0000-0001-9182-6964
Danilo BuonsensoDepartment of Woman and Child Health and Public Health, Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0001-8567-2639
Savino SpadaroAnesthesiology and Intensive Care, Department of Translational Medicine, Faculty of Medicine and Surgery, University of Ferrara, 44121 Ferrara, Italy.ORCID 0000-0001-5027-5318
Domenico Luca GriecoDepartment of Anesthesiology and Intensive Care Medicine, Catholic University of The Sacred Heart, 00168 Rome, Italy.ORCID 0000-0002-4557-6308
Maria De MartinoDepartment of Medicine, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-0445-9578
Miriam IsolaDepartment of Medicine, University of Udine, 33100 Udine, Italy.ORCID 0000-0002-6391-1720
Francesco MojoliAnesthesia and Intensive Care, Fondazione IRCCS Policlinico S. Matteo, 27100 Pavia, Italy.
Massimo GirardisIntensive Care Unit, University Hospital of Modena, University of Modena Reggio Emilia, 41124 Modena, Italy.
Antonino GiarratanoDepartment of Surgical, Oncological and Oral Science (DiChirOnS), University of Palermo, 90127 Palermo, Italy.
Elena Giovanna BignamiAnesthesiology, Critical Care and Pain Medicine Division, Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy.
Paolo NavalesiInstitute of Anaesthesia and Intensive Care, Padua University Hospital, 35128 Padua, Italy.
Maurizio CecconiDepartment of Biomedical Sciences, Humanitas University, 20072 Milan, Italy.
Salvatore Maurizio MaggioreDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-1828-9143
On Behalf Of The Italian Odissea Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInvestigating the health-related quality of life (HRQoL) after intensive care unit (ICU) discharge is necessary to identify possible modifiable risk factors. The primary aim of this study was to investigate the HRQoL in COVID-19 critically ill patients one year after ICU discharge.

methodsIn this multicenter prospective observational study, COVID-19 patients admitted to nine ICUs from 1 March 2020 to 28 February 2021 in Italy were enrolled. One year after ICU discharge, patients were required to fill in short-form health survey 36 (SF-36) and impact of event-revised (IES-R) questionnaire. A multivariate linear or logistic regression analysis to search for factors associated with a lower HRQoL and post-traumatic stress disorded (PTSD) were carried out, respectively.

resultsAmong 1003 patients screened, 343 (median age 63 years [57-70]) were enrolled. Mechanical ventilation lasted for a median of 10 days [2-20]. Physical functioning (PF 85 [60-95]), physical role (PR 75 [0-100]), emotional role (RE 100 [33-100]), bodily pain (BP 77.5 [45-100]), social functioning (SF 75 [50-100]), general health (GH 55 [35-72]), vitality (VT 55 [40-70]), mental health (MH 68 [52-84]) and health change (HC 50 [25-75]) describe the SF-36 items. A median physical component summary (PCS) and mental component summary (MCS) scores were 45.9 (36.5-53.5) and 51.7 (48.8-54.3), respectively, considering 50 as the normal value of the healthy general population. In all, 109 patients (31.8%) tested positive for post-traumatic stress disorder, also reporting a significantly worse HRQoL in all SF-36 domains. The female gender, history of cardiovascular disease, liver disease and length of hospital stay negatively affected the HRQoL. Weight at follow-up was a risk factor for PTSD (OR 1.02,

conclusionsThe HRQoL in COVID-19 ARDS (C-ARDS) patients was reduced regarding the PCS, while the median MCS value was slightly above normal. Some risk factors for a lower HRQoL have been identified, the presence of PTSD is one of them. Further research is warranted to better identify the possible factors affecting the HRQoL in C-ARDS.

Indexed as

ARDSCOVID-19health related quality of lifeICUimpact of event scale-revisedpost-traumatic stress disorderSF-36

Identifiers

PMID36769705
PMCPMC9918008

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