Evidence map›Paper›PMID 36769700›Full record

ArticleJournal of clinical medicine2023

Initial In-Hospital Visit-to-Visit Heart Rate Variability Is Associated with Higher Risk of Atrial Fibrillation in Patients with Acute Ischemic Stroke.

Jiann-Der Lee, Ya-Wen Kuo, Chuan-Pin Lee, Yen-Chu Huang, Meng Lee, Tsong-Hai Lee

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Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Jiann-Der LeeDepartment of Neurology, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan.ORCID 0000-0001-6310-0488
Ya-Wen KuoDepartment of Nursing, Chang Gung University of Science and Technology, Chiayi Campus, Chiayi 613, Taiwan.ORCID 0000-0002-9144-3880
Chuan-Pin LeeHealth Information and Epidemiology Laboratory, Chang Gung Memorial Hospital, Chiayi 613, Taiwan.
Yen-Chu HuangDepartment of Neurology, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan.ORCID 0000-0001-7885-6376
Meng LeeDepartment of Neurology, Chiayi Chang Gung Memorial Hospital, Chiayi 613, Taiwan.
Tsong-Hai LeeCollege of Medicine, Chang Gung University, Taoyuan 333, Taiwan.

Funding

Ministry of Science and Technology MOST 110-2314-B-182-037-
6 · The paper itself

Abstract

backgroundTo evaluate the association between the visit-to-visit heart rate variability and the risk of atrial fibrillation (AF) in acute ischemic stroke (AIS).

methodsWe analyzed the data of 8179 patients with AIS. Patients without AF on 12-lead electrocardiography underwent further 24 h Holter monitoring. They were categorized into four subgroups according to the visit-to-visit heart rate variability expressed as the coefficient of variation in heart rate (HR-CV). Odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using the HR-CV < 0.08 subgroup as a reference.

resultsThe adjusted OR of paroxysmal AF was 1.866 (95% CI = 1.205-2.889) for the HR-CV ≥ 0.08 and <0.10 subgroup, 1.889 (95% CI = 1.174-3.038) for the HR-CV ≥ 0.10 and <0.12 subgroup, and 5.564 (95% CI = 3.847-8.047) for the HR-CV ≥ 0.12 subgroup. The adjusted OR of persistent AF was 2.425 (95% CI = 1.921-3.062) for the HR-CV ≥ 0.08 and <0.10 subgroup, 4.312 (95% CI = 3.415-5.446) for the HR-CV ≥ 0.10 and <0.12 subgroup, and 5.651 (95% CI = 4.586-6.964) for the HR-CV ≥ 0.12 subgroup.

conclusionsHR-CV can facilitate the identification of patients with AIS at a high risk of paroxysmal AF.

Indexed as

acute ischemic strokeatrial fibrillationheart rate variability

Identifiers

PMID36769700
PMCPMC9918220

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