Evidence map›Paper›PMID 36769648›Full record

ArticleJournal of clinical medicine2023

Mid-Term Sequelae of Surviving Patients Hospitalized in Intensive Care Unit for COVID-19 Infection: The REHCOVER Study.

Marie Berger, Delphine Daubin, Jeremy Charriot, Kada Klouche, Vincent Le Moing, David Morquin, Laurence Halimi, Audrey Jaussent, Patrice Taourel, Maurice Hayot and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04443257 (REassessement After Hospitalization for Sars-COV-2 Infection), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04443257 terminatednot on this map

REassessement After Hospitalization for Sars-COV-2 Infection : Standardized Assessment of Sequelae and Comorbidities 3 to 6 Months After Hospitalization

TypeobservationalSponsorUniversity Hospital, MontpellierRan2020 to 2022Enrolled119ConditionsSars-CoV2Armsassessment of the sequelae after hospitalization for Sars-COV-2
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Cardiopulmonary Complications after Pulmonary Embolism in COVID-19.International journal of molecular sciences · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Marie BergerDepartment of Internal Medicine, Montpellier University Hospital, 34090 Montpellier, France.
Delphine DaubinCritical Care Unit, Montpellier University Hospital, 34090 Montpellier, France.
Jeremy CharriotDepartment of Respiratory Diseases, Montpellier University Hospital, 34090 Montpellier, France.ORCID 0000-0002-1420-5774
Kada KloucheCritical Care Unit, Montpellier University Hospital, 34090 Montpellier, France.
Vincent Le MoingFaculty of Medicine, University of Montpellier, 34090 Montpellier, France.ORCID 0000-0002-9529-2792
David MorquinDepartment of Infectious Diseases, Montpellier University Hospital, 34090 Montpellier, France.
Laurence HalimiDepartment of Respiratory Diseases, Montpellier University Hospital, 34090 Montpellier, France.ORCID 0000-0002-0567-1191
Audrey JaussentClinical Research and Epidemiology Unit, Montpellier University Hospital, 34090 Montpellier, France.
Patrice TaourelFaculty of Medicine, University of Montpellier, 34090 Montpellier, France.
Maurice HayotPhyMedExp, INSERM U1046, CNRS UMR 9214, University of Montpellier, 34295 Montpellier, France.ORCID 0000-0001-6388-1114
Jean-Paul CristolPhyMedExp, INSERM U1046, CNRS UMR 9214, University of Montpellier, 34295 Montpellier, France.ORCID 0000-0001-8563-7278
Nicolas NagotFaculty of Medicine, University of Montpellier, 34090 Montpellier, France.
Pierre FeslerDepartment of Internal Medicine, Montpellier University Hospital, 34090 Montpellier, France.ORCID 0000-0002-7831-6545
Camille RoubilleDepartment of Internal Medicine, Montpellier University Hospital, 34090 Montpellier, France.ORCID 0000-0002-5268-1704

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objective of this prospective, single-center study was to explore the mid-term outcomes 6 to 9 months after hospitalization in an Intensive Care Unit (ICU) for severe COVID-19 infection.

methodsPatients systematically underwent biological tests, pulmonary function tests, chest computed tomography (CT) scan, and psychological tests.

resultsAmong 86 patients, including 71 (82.6%) men, median age of 65.8 years (56.7; 72.4), 57 (71.3%) patients presented post-COVID-19 asthenia, 39 (48.1%) muscle weakness, and 30 (36.6%) arthralgia. Fifty-two (64.2%) patients had a decreased diffusion capacity for carbon monoxide (DLCO) <80% and 16 (19.8%) had DLCO <60%. Chest CT-scans showed ground glass opacities in 35 (40.7%) patients, and reticular changes in 28 patients (33.7%), including fibrosis-like changes in 18 (21.7%) patients. Reticular changes and DLCO <60% were associated with length of stay in ICU, and reticular changes with higher maximal CRP level. The psychological questionnaires found 37.7% suffered from depression, 23.5% from anxiety, 42.4% from insomnia, and 9.4% from post-traumatic stress. Being female was associated with a higher frequency of depression and anxiety, with depression scores being associated with obesity.

conclusionsMany patients hospitalized in ICU for severe COVID-19 infection have mid-term sequelae. Additional studies on the prognostic factors seem necessary.

Indexed as

COVID-19intensive caremid-term outcomesSARS-COV-2sequelae

Identifiers

PMID36769648
PMCPMC9917891

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.