ArticleJournal of clinical medicine2023
Morbidity Associated with Chronic Hyponatremia.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Copeptin kinetics in healthy aging.The Journal of clinical endocrinology and metabolism · 2026Trial
- Importance of Capillary Leak and Nocturia in Defining and Successfully Treating Idiopathic Edema.Journal of clinical medicine · 2025Review
- Exertional hyponatremia among active component members of the U.S. Armed Forces, 2009-2024.MSMR · 2025Article
- Hyponatremia in geriatric patients.Zeitschrift fur Gerontologie und Geriatrie · 2025Article
- Associations between serum sodium level ranges with geriatric syndromes.European geriatric medicine · 2025Article
- Effects of Loading Forces, Loading Positions, and Splinting of Two, Three, or Four Ti-Zr (RoxolidJournal of functional biomaterials · 2024Article
- Chronic Hyponatremia: The Role of Reset Osmostat in Patients with Suspected SIAD.Journal of clinical medicine · 2024Article
- [Consensus recommendations on the diagnosis and treatment of hyponatremia from the Austrian Society for Nephrology 2024].Wiener klinische Wochenschrift · 2024Article
- Associations between Baseline Hyponatremia and Activities of Daily Living and Muscle Health in Convalescent Stroke Patients.Progress in rehabilitation medicine · 2024Article
- Thalamic Neuron Resilience during Osmotic Demyelination Syndrome (ODS) Is Revealed by Primary Cilium Outgrowth and ADP-ribosylation factor-like protein 13B Labeling in Axon Initial Segment.International journal of molecular sciences · 2023Article
- Mildly Low Serum Sodium Levels in Chronic Liver Disease: At Risk for Sarcopenia and Portal Hypertension.Cureus · 2023Article
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Authors and funding
1 author.
Funding
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Abstract
This article will discuss the consequences of chronic hyponatremia. In conditions such as cancer, heart failure, liver cirrhosis, or chronic kidney disease, the presence and magnitude of hypotonic hyponatremia are considered to reflect the severity of the underlying disease and are associated with increased morbidity as well as mortality. Hyponatremia can be acute (<48 h) or chronic (>2-3 days). Chronic hyponatremia is associated with attention deficit, dizziness, tiredness, gait disturbance, falls, sarcopenia, bone fractures, osteoporosis, hypercalciuria (in the syndrome of inappropriate antidiuresis-SIADH), and kidney stones. In vitro studies have shown that cells grown in a low concentration of extracellular sodium have a greater proliferation rate and motility. Patients with chronic hyponatremia are more likely to develop cancer. We will not review the clinical consequences of respiratory arrest and osmotic demyelination syndrome (ODS) of the too-late or excessive treatment of hyponatremia.
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