Evidence map›Paper›PMID 36769525›Full record

ArticleJournal of clinical medicine2023

Assessment of Clinical Indicators Registered on Admission to the Hospital Related to Mortality Risk in Cancer Patients with COVID-19.

Alina Szewczyk-Dąbrowska, Mirosław Banasik, Krystyna Dąbrowska, Krzysztof Kujawa, Wojciech Bombala, Agata Sebastian, Agnieszka Matera-Witkiewicz, Magdalena Krupińska, Urszula Grata-Borkowska, Janusz Sokołowski and 8 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Alina Szewczyk-DąbrowskaDepartment of Family Medicine, Wroclaw Medical University, Syrokomli Street 1, 51-141 Wroclaw, Poland.ORCID 0000-0001-7629-4912
Mirosław BanasikClinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.ORCID 0000-0002-0588-1551
Krystyna DąbrowskaRegional Specialist Hospital in Wroclaw, Research and Development Center, Kamieńskiego 73a, 51-124 Wroclaw, Poland.ORCID 0000-0002-1518-3183
Krzysztof KujawaStatistical Analysis Centre, Wroclaw Medical University, K. Marcinkowski Street 2-6, 50-368 Wroclaw, Poland.ORCID 0000-0003-2812-4702
Wojciech BombalaStatistical Analysis Centre, Wroclaw Medical University, K. Marcinkowski Street 2-6, 50-368 Wroclaw, Poland.
Agata SebastianClinical Department of Rheumatology and Internal Medicine, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Agnieszka Matera-WitkiewiczScreening of Biological Activity Assays and Collection of Biological Material Laboratory, Wroclaw Medical University, Borowska Street 211a, 50-556 Wroclaw, Poland.ORCID 0000-0002-1064-1237
Magdalena KrupińskaScreening of Biological Activity Assays and Collection of Biological Material Laboratory, Wroclaw Medical University, Borowska Street 211a, 50-556 Wroclaw, Poland.
Urszula Grata-BorkowskaDepartment of Family Medicine, Wroclaw Medical University, Syrokomli Street 1, 51-141 Wroclaw, Poland.ORCID 0000-0003-3783-0481
Janusz SokołowskiClinical Department of Emergency Medicine, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Katarzyna Kiliś-PstrusińskaClinical Department of Paediatric Nephrology, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.ORCID 0000-0001-7352-6992
Barbara AdamikClinical Department of Anaesthesiology and Intensive Therapy, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.ORCID 0000-0002-0541-841X
Adrian DoroszkoClinical Department of Internal and Occupational Diseases, Hypertension and Clinical Oncology, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.ORCID 0000-0001-5472-028X
Krzysztof KaliszewskiClinical Department of General, Minimally Invasive and Endocrine Surgery, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.ORCID 0000-0002-3291-5294
Michał PomorskiClinical Department of Gynecology and Obstetrics, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Marcin ProtasiewiczInstitute of Heart Diseases, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Ewa A JankowskaInstitute of Heart Diseases, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.
Katarzyna MadziarskaClinical Department of Nephrology and Transplantation Medicine, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.ORCID 0000-0002-3624-3691

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOncology patients are a particularly vulnerable group to the severe course of COVID-19 due to, e.g., the suppression of the immune system. The study aimed to find links between parameters registered on admission to the hospital and the risk of later death in cancer patients with COVID-19.

methodsThe study included patients with a reported history of malignant tumor (

resultsMultivariate Cox proportional hazards models were successfully obtained for the following categories: Patient data, Comorbidities, Signs recorded on admission, Medications used before hospitalization and Laboratory results recorded on admission. With the models developed for oncology patients, we identified the following variables that registered on patients' admission were linked to significantly increased risk of death. They are: male sex, presence of metastases in neoplastic disease, impaired consciousness (somnolence or confusion), wheezes/rhonchi, the levels of white blood cells and neutrophils.

conclusionEarly identification of the indicators of a poorer prognosis may serve clinicians in better tailoring surveillance or treatment among cancer patients with COVID-19.

Indexed as

cancerCOVID-19infectious diseasesmortality riskprognosis

Identifiers

PMID36769525
PMCPMC9917478

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.