ArticleJournal of clinical medicine2023
Stressor-Specific Sex Differences in Amygdala-Frontal Cortex Networks.
Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Contextualizing the adolescent social brain: Links to social health using data from the Adolescent Brain Cognitive Development Study.Developmental cognitive neuroscience · 2026Article
- Incomplete network restoration may be associated with higher relapse risk in women with major depressive disorder.Psychiatry and clinical neurosciences · 2026Article
- Amygdala reactivity to social stress in young adults: A scoping review of neuroimaging studies.Neurobiology of stress · 2026Review
- Personalized resilience: how individual variability in brain-immune responses to stress influences the development of anxiety disorders.Frontiers in cellular neuroscience · 2026Review
- Social stress, cortisol awakening response and sex: association with hippocampus and amygdala volume.Biology of sex differences · 2025Article
- Associations between suicidal ideation and childhood maltreatment as well as inflammatory cytokines in adolescents with major depressive disorder.European archives of psychiatry and clinical neuroscience · 2025Article
- The associations of suicidal ideation with psychopathology and inflammatory cytokines in patients with chronic schizophrenia.BMC psychiatry · 2025Article
- Caregiver or Playmate? Fathers' and mothers' brain responses to ball-play with children.Cognitive, affective & behavioral neuroscience · 2025Article
- Sex Differences in the Neuroendocrine Stress Response: A View from a CRH-Reporting Mouse Line.International journal of molecular sciences · 2024Article
- Addressing the gender paradox: Effective suicide prevention strategies for women.Cell reports. Medicine · 2024Review
- Testosterone and the Amygdala's Functional Connectivity in Women and Men.Journal of clinical medicine · 2023Article
- Neural response to stress differs by sex in young adulthood.Psychiatry research. Neuroimaging · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
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Abstract
Females and males differ in stress reactivity, coping, and the prevalence rates of stress-related disorders. According to a neurocognitive framework of stress coping, the functional connectivity between the amygdala and frontal regions (including the dorsolateral prefrontal cortex (dlPFC), ventral anterior cingulate cortex (vACC), and medial prefrontal cortex (mPFC)) plays a key role in how people deal with stress. In the current study, we investigated the effects of sex and stressor type in a within-subject counterbalanced design on the resting-state functional connectivity (rsFC) of the amygdala and these frontal regions in 77 healthy participants (40 females). Both stressor types led to changes in subjective ratings, with decreasing positive affect and increasing negative affect and anger. Females showed higher amygdala-vACC and amygdala-mPFC rsFC for social exclusion than for achievement stress, and compared to males. Whereas a higher amygdala-vACC rsFC indicates the activation of emotion processing and coping, a higher amygdala-mPFC rsFC indicates feelings of reward and social gain, highlighting the positive effects of social affiliation. Thus, for females, feeling socially affiliated might be more fundamental than for males. Our data indicate interactions of sex and stressor in amygdala-frontal coupling, which translationally contributes to a better understanding of the sex differences in prevalence rates and stress coping.
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