Evidence map›Paper›PMID 36769475›Full record

ArticleJournal of clinical medicine2023

The Importance of New EBMT Criteria on the Diagnosis of Veno-Occlusive Liver Disease in Children.

Mária Füssiová, Peter Švec, Júlia Horáková, Petr Sedláček, Peter Rohoň, Peter Celec, Ivana Boďová, Jaroslava Adamčáková, Tomáš Sýkora, Veronika Dobšinská and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mária FüssiováBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University, 833 40 Bratislava, Slovakia.
Peter ŠvecBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University, 833 40 Bratislava, Slovakia.ORCID 0000-0002-7647-2253
Júlia HorákováBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University, 833 40 Bratislava, Slovakia.
Petr SedláčekDepartment of Pediatric Hematology and Oncology, Charles University Motol, 150 06 Prague, Czech Republic.ORCID 0000-0001-7895-2886
Peter RohoňDepartment of Hematology and Transfusion, Faculty of Medicine, Comenius University, 812 50 Bratislava, Slovakia.
Peter CelecInstitute of Molecular Biomedicine, Faculty of Medicine, Comenius University, 811 08 Bratislava, Slovakia.ORCID 0000-0001-5883-3580
Ivana BoďováBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University, 833 40 Bratislava, Slovakia.
Jaroslava AdamčákováBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University, 833 40 Bratislava, Slovakia.
Tomáš SýkoraBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University, 833 40 Bratislava, Slovakia.
Veronika DobšinskáBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University, 833 40 Bratislava, Slovakia.
Miroslava PozdechováBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University, 833 40 Bratislava, Slovakia.
Dominika DóczyováBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University, 833 40 Bratislava, Slovakia.
Santia VargováBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University, 833 40 Bratislava, Slovakia.
Alexandra KolenováBone Marrow Transplantation Unit, Department of Pediatric Hematology and Oncology, National Institute of Children's Diseases, Comenius University, 833 40 Bratislava, Slovakia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly recognition and specific therapy facilitate a favorable disease course in hepatic venous-occlusive disease (HVOD) following hematopoietic stem cell transplantation (HCT). Diagnostic and classification criteria, published by the European Society for Blood and Marrow Transplantation (EBMT), better account for clinical differences in disease presentation in pediatric populations.

objectivesTo compare the course of HVOD in children before and after the implementation of new EBMT criteria. MATERIAL AND

methodsThe study retrospectively evaluates 26 HVODs in 179 children treated in a single HCT unit (Slovakia) comparing the period of 2014-2017 using the Baltimore and modified Seattle criteria with the period of 2018-2021, when new EBMT criteria were adopted.

resultsNo difference in HVOD incidence (11.2% vs. 14.8%,

conclusionsDifferent time periods around the implementation of new criteria are evaluated, underling that pediatric EBMT criteria for post-transplant HVOD diagnosis appear more sensitive.

Indexed as

hematopoietic stem cell transplantationnew diagnostic and severity EBMT criteria in childhoodretrospective analysisveno-occlusive disease of the liver

Identifiers

PMID36769475
PMCPMC9918163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.