ReviewJournal of clinical medicine2023
Effects of Physiotherapy on Pain and Mouth Opening in Temporomandibular Disorders: An Umbrella and Mapping Systematic Review with Meta-Meta-Analysis.
Review in Journal of clinical medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Comparison of the effectiveness of three different conservative methods in myogenous temporomandibular disorders.Revista da Associacao Medica Brasileira (1992) · 2025Trial
- Multimorbidity in Chronic Overlapping Pain Conditions: From Burden to Integrated Care.Journal of clinical medicine · 2026Review
- Review
- Dentists' awareness in Kuwait of the role of physical therapy management of temporomandibular joint disorders: a cross-sectional study.BMC oral health · 2025Article
- Regional cutaneous and muscle sensitivity does not mediate changes in active mouth opening in temporomandibular disorders: a cross-sectional study.Journal of oral & facial pain and headache · 2025Article
- Multimodal Approaches in the Management of Temporomandibular Disorders: A Narrative Review.Journal of clinical medicine · 2025Review
- Preclinical evaluation of dose-dependent effects of photobiomodulation therapy on persistent inflammation in the temporomandibular joint.Journal of oral & facial pain and headache · 2025Article
- Anterior Disc Displacement of Temporomandibular Joint: Imaging Diagnosis and Multidisciplinary Treatment.International journal of general medicine · 2025Review
- Efficacy of massage versus massage with post isometric relaxation in temporomandibular disorders: a randomized controlled trial.BMC sports science, medicine & rehabilitation · 2024Article
- Current Clinical Research Directions on Temporomandibular Joint Intra-Articular Injections: A Mapping Review.Journal of clinical medicine · 2023Review
- Injectable Platelet-Rich Fibrin (I-PRF) Administered to Temporomandibular Joint Cavities: A Scoping Review.Journal of clinical medicine · 2023Article
- Correlation between Temporomandibular Disorders (TMD) and Posture Evaluated trough the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD): A Systematic Review with Meta-Analysis.Journal of clinical medicine · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this meta-meta-analysis was to assess the current evidence regarding the effect of physical therapy (PT) interventions on pain and functional variables in temporomandibular disorders (TMD). We conducted an umbrella systematic review (SR) and four meta-meta-analyses (MMA) and created an evidence map to determine the effectiveness of PT on pain intensity and maximum mouth opening in patients with TMD. The quality of the included SR was assessed with the AMSTAR 2, and the risk of bias with ROBIS. Of the 31 SR included in the umbrella SR, only 10 were included in the MMA. The MMA showed moderate effects for manual therapy and therapeutic exercise, and large effects for low-level laser therapy on improving pain intensity and maximum mouth opening in patients with TMD, with a limited to moderate quality of evidence. The overlapping analyses showed only a slight overlap for all the MMA according to the corrected covered area (range from 0.07 to 0.2), 23.1% to 41.6%. This umbrella SR showed that manual therapy and exercise interventions, as well as low-level laser therapy interventions, are effective in the reduction in pain intensity and improvement of maximum mouth opening in TMD. This article presents a synthesis of the available evidence related to the various physical therapy interventions used in patients presenting with temporomandibular disorders. These results could help clinicians to select the optimal intervention for their patients and to reject those that are less useful.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.