Evidence map›Paper›PMID 36769275›Full record

ArticleInternational journal of molecular sciences2023

Design, Synthesis and Antimicrobial Evaluation of New

Petr Šlechta, Adam Anthony Needle, Ondřej Jand'ourek, Pavla Paterová, Klára Konečná, Pavel Bárta, Jiří Kuneš, Vladimír Kubíček, Martin Doležal, Marta Kučerová-Chlupáčová

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Identification of novelFuture medicinal chemistry · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Petr ŠlechtaDepartment of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy in Hradec Králové, Charles University, 500 05 Hradec Králové, Czech Republic.ORCID 0000-0002-7814-9353
Adam Anthony NeedleDepartment of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy in Hradec Králové, Charles University, 500 05 Hradec Králové, Czech Republic.
Ondřej Jand'ourekDepartment of Biological and Medical Sciences, Faculty of Pharmacy in Hradec Králové, Charles University, 500 05 Hradec Králové, Czech Republic.ORCID 0000-0003-4633-2062
Pavla PaterováDepartment of Clinical Microbiology, University Hospital, 500 05 Hradec Králové, Czech Republic.ORCID 0000-0003-0192-7345
Klára KonečnáDepartment of Biological and Medical Sciences, Faculty of Pharmacy in Hradec Králové, Charles University, 500 05 Hradec Králové, Czech Republic.ORCID 0000-0001-5670-7767
Pavel BártaDepartment of Biophysics and Physical Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, 500 05 Hradec Králové, Czech Republic.ORCID 0000-0001-5445-5658
Jiří KunešDepartment of Organic and Bioorganic Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, 500 05 Hradec Králové, Czech Republic.
Vladimír KubíčekDepartment of Biophysics and Physical Chemistry, Faculty of Pharmacy in Hradec Králové, Charles University, 500 05 Hradec Králové, Czech Republic.
Martin DoležalDepartment of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy in Hradec Králové, Charles University, 500 05 Hradec Králové, Czech Republic.ORCID 0000-0003-1558-6625
Marta Kučerová-ChlupáčováDepartment of Pharmaceutical Chemistry and Pharmaceutical Analysis, Faculty of Pharmacy in Hradec Králové, Charles University, 500 05 Hradec Králové, Czech Republic.ORCID 0000-0002-8656-0740
Charles University · CZUniversity Hospital Hradec Králové · CZ

Funding

Charles University SVV 260 547Ministry of Health of the Czech Republic NU21-05-00482
6 · The paper itself

Abstract

Tuberculosis remains a serious killer among infectious diseases due to its incidence, mortality, and occurrence of resistant mycobacterial strains. The challenge to discover new antimycobacterial agents forced us to prepare a series of

Indexed as

Amino Acyl-tRNA SynthetasesAnti-Infective AgentsMycobacterium tuberculosisAmidesAnti-Bacterial AgentsAntitubercular AgentsFungiHumansMicrobial Sensitivity TestsMolecular Docking SimulationStructure-Activity RelationshipAmidesAmino Acyl-tRNA SynthetasesAnti-Bacterial AgentsAnti-Infective AgentsAntitubercular Agentsantimicrobialantimycobacterialbenzoxaborolecytotoxicitymolecular dockingmultidrug-resistant tuberculosistuberculosis

Identifiers

PMID36769275
PMCPMC9917560
OpenAlexW4319158677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.