Evidence map›Paper›PMID 36769208›Full record

ArticleInternational journal of molecular sciences2023

Brain N-Glycosylation and Lipidomic Profile Changes Induced by a High-Fat Diet in Dyslipidemic Hamsters.

Beatrix Paton, Elisabet Foguet-Romero, Manuel Suarez, Jordi Mayneris-Perxachs, Noemí Boqué, Antoni Caimari, Núria Canela, Pol Herrero

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Beatrix PatonEurecat, Centre Tecnològic de Catalunya, Centre for Omic Sciences, Joint Unit Eurecat-Universitat Rovira i Virgili, Unique Scientific and Technical Infrastructure (ICTS), 43204 Reus, Spain.ORCID 0000-0001-5896-5495
Elisabet Foguet-RomeroEurecat, Centre Tecnològic de Catalunya, Centre for Omic Sciences, Joint Unit Eurecat-Universitat Rovira i Virgili, Unique Scientific and Technical Infrastructure (ICTS), 43204 Reus, Spain.
Manuel SuarezNutrigenomics Research Group, Departament de Bioquímica i Biotecnologia, Universitat Rovira i Virgili, 43007 Tarragona, Spain.ORCID 0000-0003-0122-8253
Jordi Mayneris-PerxachsDepartment of Diabetes, Endocrinology and Nutrition, Girona Biomedical Research Centre (IDIBGI), Hospital Universitari de Girona Doctor Josep Trueta, 17190 Girona, Spain.ORCID 0000-0003-3788-3815
Noemí BoquéEurecat, Centre Tecnològic de Catalunya, Technological Unit of Nutrition and Health, 43204 Reus, Spain.ORCID 0000-0001-7173-5512
Antoni CaimariEurecat, Centre Tecnològic de Catalunya, Biotechnology Area, 43204 Reus, Spain.ORCID 0000-0001-6144-0294
Núria CanelaEurecat, Centre Tecnològic de Catalunya, Centre for Omic Sciences, Joint Unit Eurecat-Universitat Rovira i Virgili, Unique Scientific and Technical Infrastructure (ICTS), 43204 Reus, Spain.ORCID 0000-0003-0261-2396
Pol HerreroEurecat, Centre Tecnològic de Catalunya, Centre for Omic Sciences, Joint Unit Eurecat-Universitat Rovira i Virgili, Unique Scientific and Technical Infrastructure (ICTS), 43204 Reus, Spain.

Funding

Centre for the Development of Industrial Technology (CDTI) of the Spanish Ministry of Sci-ence and Innovation CER-2019-1010
6 · The paper itself

Abstract

The consumption of diets rich in saturated fats is known to be associated with higher mortality. The adoption of healthy habits, for instance adhering to a Mediterranean diet, has proved to exert a preventive effect towards cardiovascular diseases and dyslipidemia. Little is known about how a suboptimal diet can affect brain function, structure, and the mechanisms involved. The aims of this study were to examine how a high-fat diet can alter the brain N-glycan and lipid profile in male Golden Syrian hamsters and to evaluate the potential of a Mediterranean-like diet to reverse this situation. During twelve weeks, hamsters were fed a normal fat diet (CTRL group), a high-fat diet (HFD group), and a high-fat diet followed by a Mediterranean-like diet (MED group). Out of seventy-two identified N-glycans, fourteen were significant (

Indexed as

Diet, High-FatDyslipidemiasAnimalsBrainCricetinaeDietary FatsGlycosylationLipidomicsLiverMaleMesocricetusDietary Fatsbrain glycosylationdyslipidemiahigh-fat dietlipidomicsmass spectrometrymediterranean dietN-glycan

Identifiers

PMID36769208
PMCPMC9918045

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.