Evidence map›Paper›PMID 36769145›Full record

ArticleInternational journal of molecular sciences2023

Identification of Novel Sphydrofuran-Derived Derivatives with Lipid-Lowering Activity from the Active Crude Extracts of

Yuhong Tian, Yongjun Jiang, Zhengshun Wen, Liping Guan, Xiaokun Ouyang, Wanjing Ding, Zhongjun Ma

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuhong TianSchool of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Yongjun JiangSchool of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.ORCID 0000-0001-5419-7345
Zhengshun WenSchool of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Liping GuanSchool of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.
Xiaokun OuyangSchool of Food and Pharmacy, Zhejiang Ocean University, Zhoushan 316022, China.ORCID 0000-0002-8534-0279
Wanjing DingInstitute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, Zhoushan 316021, China.
Zhongjun MaInstitute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, Zhoushan 316021, China.

Funding

Basic Public Welfare Research Project of Zhejiang Province LGF22H300005general research project of Education Department of Zhejiang Province Y202147485the Key Research and development Program of "Leading Goose" of Zhejiang Province 2022C02059Zhejiang Provincial Leading Innovation and Entrepreneurship Team Project 2020R01015
6 · The paper itself

Abstract

Lipid-lowering is one of the most effective methods of prevention and treatment for cardiovascular diseases. However, most clinical lipid-lowering drugs have adverse effects and cannot achieve the desired efficacy in some complex hyperlipidemia patients, so it is of great significance to develop safe and effective novel lipid-lowering drugs. In the course of our project aimed at discovering the chemical novelty and bioactive natural products of marine-derived actinomycetes, we found that the organic crude extracts (OCEs) of

Indexed as

GlycerolNocardiopsisAnimalsHypolipidemic AgentsLipidsMicePlant ExtractsGlycerolHypolipidemic AgentsLipidsPlant Extractssphydrofuranlipid-loweringNocardiopsis sp.sphydrofuran derivativesstructure elucidation

Identifiers

PMID36769145
PMCPMC9917766

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.