Evidence map›Paper›PMID 36769132›Full record

ArticleInternational journal of molecular sciences2023

Prevalence of Transient Hypothyroidism in Children Diagnosed with Congenital Hypothyroidism between 2000 and 2016.

Sabrina Gmür, Daniel Konrad, Ralph Fingerhut

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. History of Neonatal Screening of Congenital Hypothyroidism in Portugal.International journal of neonatal screening · 2024
    Article
  7. Evaluation of Transient or Permanent Congenital Hypothyroidism.Journal of clinical practice and research · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sabrina GmürDepartment of Endocrinology & Diabetology, University Children's Hospital Zurich, University of Zurich, CH-8032 Zurich, Switzerland.
Daniel KonradDepartment of Endocrinology & Diabetology, University Children's Hospital Zurich, University of Zurich, CH-8032 Zurich, Switzerland.ORCID 0000-0001-9067-4356
Ralph FingerhutChildren's Research Center, University Children's Hospital Zurich, University of Zurich, CH-8032 Zurich, Switzerland.ORCID 0000-0002-9674-8931

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Newborn screening (NBS) for congenital hypothyroidism (CH) was introduced in Switzerland in 1977, which allowed for the preclinical, biochemical diagnosis. The aim of this study was to evaluate the prevalence of transient CH (tCH) in the canton of Zurich. In this analytical cohort study, all newborns born in the canton of Zurich, between the 1st of January 2000 and the 30st of June 2016, with a TSH value above 15 mU/L (whole blood) were included. There were 115 cases out of 247,918 babies born during the study period. However, 23 cases had to be excluded due to missing data. The definite diagnosis was made after a thyroxine withdrawal at 2 years of age. The total prevalence of confirmed CH and the female to male ratio (f/m) were 1:2695 and 2.17:1; for permanent CH (pCH), 1:3443 and 2.8:1; and for tCH, 1:12,396 and 1:1, respectively. The TSH value was significantly higher in pCH compared to tCH, at 130.3 (62.9-171.9) and 36.4 (26.5-53.3) (median and interquartile range), respectively (

Indexed as

Congenital HypothyroidismChildCohort StudiesFemaleHumansInfantInfant, NewbornMaleNeonatal ScreeningPrevalenceThyrotropinThyroxineThyrotropinThyroxinecongenital hypothyroidism (CH)dried blood sample (DBS)newborn screening (NBS)prematuritythyroid stimulating hormone (TSH)total thyroxine (TT4)

Identifiers

PMID36769132
PMCPMC9917150

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.