Evidence map›Paper›PMID 36769051›Full record

ArticleInternational journal of molecular sciences2023

Retinal Tissue Shows Glial Changes in a Dravet Syndrome Knock-in Mouse Model.

Juan J Salazar, Andrea Satriano, José A Matamoros, José A Fernández-Albarral, Elena Salobrar-García, Inés López-Cuenca, Rosa de Hoz, Lidia Sánchez-Puebla, José M Ramírez, Cristina Alonso and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Dravet syndrome: novel insights intoFrontiers in neuroscience · 2025
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Juan J SalazarInstituto de Investigaciones Oftalmológicas Ramón Castroviejo, Grupo UCM 920105, IdISSC, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0001-5480-5902
Andrea SatrianoPreclinical and Translational Pharmacology, Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.ORCID 0000-0003-1279-842X
José A MatamorosInstituto de Investigaciones Oftalmológicas Ramón Castroviejo, Grupo UCM 920105, IdISSC, Universidad Complutense de Madrid, 28040 Madrid, Spain.
José A Fernández-AlbarralInstituto de Investigaciones Oftalmológicas Ramón Castroviejo, Grupo UCM 920105, IdISSC, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0003-0399-7996
Elena Salobrar-GarcíaInstituto de Investigaciones Oftalmológicas Ramón Castroviejo, Grupo UCM 920105, IdISSC, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0001-5939-5551
Inés López-CuencaInstituto de Investigaciones Oftalmológicas Ramón Castroviejo, Grupo UCM 920105, IdISSC, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0003-0511-515X
Rosa de HozInstituto de Investigaciones Oftalmológicas Ramón Castroviejo, Grupo UCM 920105, IdISSC, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0002-1581-087X
Lidia Sánchez-PueblaInstituto de Investigaciones Oftalmológicas Ramón Castroviejo, Grupo UCM 920105, IdISSC, Universidad Complutense de Madrid, 28040 Madrid, Spain.
José M RamírezInstituto de Investigaciones Oftalmológicas Ramón Castroviejo, Grupo UCM 920105, IdISSC, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0002-5145-5094
Cristina AlonsoCentro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, 28031 Madrid, Spain.
Valentina SattaCentro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, 28031 Madrid, Spain.
Inés Hernández-FisacCentro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, 28031 Madrid, Spain.
Onintza SagredoCentro de Investigación Biomédica en Red en Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, 28031 Madrid, Spain.
Ana I RamírezInstituto de Investigaciones Oftalmológicas Ramón Castroviejo, Grupo UCM 920105, IdISSC, Universidad Complutense de Madrid, 28040 Madrid, Spain.ORCID 0000-0002-2656-4723

Funding

Complutense University of Madrid CT42/18-CT43/18Complutense University of Madrid CT58/21-CT59/21Complutense University of Madrid CT82/20-CT83/20Instituto de Salud Carlos III PI20/00773Ministerio de Ciencia e Innovación RED2018-102499-T (RETIBRAIN)Ministerior de Ciencia, Innovación y Universidades FPU17/01023
6 · The paper itself

Abstract

Dravet syndrome (DS) is an epileptic encephalopathy caused by mutations in the

Indexed as

Epilepsies, MyoclonicNAV1.1 Voltage-Gated Sodium ChannelAnimalsDisease Models, AnimalMiceMicrogliaRetinaSeizuresNAV1.1 Voltage-Gated Sodium ChannelScn1a protein, mouseastrocytesDravet syndromeGABAergic amacrine cellsmicrogliaretinaretinal ganglion cellsSyn-Cre/Scn1aWT/A1783V mice

Identifiers

PMID36769051
PMCPMC9916888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.