Evidence map›Paper›PMID 36769028›Full record

ArticleInternational journal of molecular sciences2023

Exploration of Novel Scaffolds Targeting Cytochrome

Cecilia Pinna, Tommaso Laurenzi, Fabio Forlani, Luca Palazzolo, Claire Beatrice Nolan, Michael S Christodoulou, Paolo Cortesi, Andrea Pinto, Ivano Eberini, Andrea Kunova and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cecilia PinnaDepartment of Food Environmental and Nutritional Science (DeFENS), University of Milan, 20133 Milano, Italy.ORCID 0000-0002-2828-5875
Tommaso LaurenziDepartment of Pharmacological and Biomolecular Sciences (DiSFeB), University of Milan, 20133 Milano, Italy.ORCID 0000-0002-0446-0392
Fabio ForlaniDepartment of Food Environmental and Nutritional Science (DeFENS), University of Milan, 20133 Milano, Italy.ORCID 0000-0001-9405-973X
Luca PalazzoloDepartment of Pharmacological and Biomolecular Sciences (DiSFeB), University of Milan, 20133 Milano, Italy.ORCID 0000-0002-5370-9588
Claire Beatrice NolanDepartment of Food Environmental and Nutritional Science (DeFENS), University of Milan, 20133 Milano, Italy.ORCID 0000-0003-0393-5701
Michael S ChristodoulouDepartment of Food Environmental and Nutritional Science (DeFENS), University of Milan, 20133 Milano, Italy.ORCID 0000-0002-5098-3143
Paolo CortesiDepartment of Food Environmental and Nutritional Science (DeFENS), University of Milan, 20133 Milano, Italy.ORCID 0000-0002-2992-4253
Andrea PintoDepartment of Food Environmental and Nutritional Science (DeFENS), University of Milan, 20133 Milano, Italy.ORCID 0000-0002-2501-3348
Ivano EberiniDepartment of Pharmacological and Biomolecular Sciences (DiSFeB), University of Milan, 20133 Milano, Italy.ORCID 0000-0001-5521-3829
Andrea KunovaDepartment of Food Environmental and Nutritional Science (DeFENS), University of Milan, 20133 Milano, Italy.ORCID 0000-0002-9210-4792
Sabrina DallavalleDepartment of Food Environmental and Nutritional Science (DeFENS), University of Milan, 20133 Milano, Italy.ORCID 0000-0002-8813-8922

Funding

Ministry of Education, Universities and Research Progetto EccellenzaUniversity of Milan SEED2019 "Dual-active hybrid fungicides against Pyricularia oryzae"
6 · The paper itself

Abstract

The fulfilment of the European "Farm to Fork" strategy requires a drastic reduction in the use of "at risk" synthetic pesticides; this exposes vulnerable agricultural sectors-among which is the European risiculture-to the lack of efficient means for the management of devastating diseases, thus endangering food security. Therefore, novel scaffolds need to be identified for the synthesis of new and more environmentally friendly fungicides. In the present work, we employed our previously developed 3D model of

Indexed as

AscomycotaFungicides, IndustrialCytochromes bElectron Transport Complex IIIStrobilurinsCytochromes bElectron Transport Complex IIIFungicides, IndustrialStrobilurinsantifungalscytochrome bc1 enzymatic inhibitiondesign and synthesishigh-throughput virtual screeningrice blast

Identifiers

PMID36769028
PMCPMC9917009

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.