Evidence map›Paper›PMID 36768918›Full record

ArticleInternational journal of molecular sciences2023

Evaluation of the Antiseizure Activity of Endemic Plant

Adrianna Skiba, Ewelina Kozioł, Simon Vlad Luca, Barbara Budzyńska, Piotr Podlasz, Wietske Van Der Ent, Elham Shojaeinia, Camila V Esguerra, Mohammed Nour, Laurence Marcourt and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 6 countries.

Adrianna SkibaDepartment of Natural Products Chemistry, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0001-6601-8295
Ewelina KoziołDepartment of Natural Products Chemistry, Medical University of Lublin, 20-093 Lublin, Poland.
Simon Vlad LucaBiothermodynamics, TUM School of Life Sciences, Technical University of Munich, 85354 Freising, Germany.ORCID 0000-0003-0904-0060
Barbara BudzyńskaIndependent Laboratory of Behavioral Studies, Medical University, Chodzki 4a, 20-090 Lublin, Poland.ORCID 0000-0001-5917-9285
Piotr PodlaszDepartment of Pathophysiology, Forensic Veterinary and Administration, Faculty of Veterinary Medicine, University of Warmia and Mazury, 10-719 Olsztyn, Poland.ORCID 0000-0002-9162-5449
Wietske Van Der EntChemical Neuroscience Group, Centre for Molecular Medicine Norway (NCMM), University of Oslo, Forskningsparken, Gaustadalleén 21, 0349 Oslo, Norway.
Elham ShojaeiniaChemical Neuroscience Group, Centre for Molecular Medicine Norway (NCMM), University of Oslo, Forskningsparken, Gaustadalleén 21, 0349 Oslo, Norway.ORCID 0000-0002-8232-9840
Camila V EsguerraChemical Neuroscience Group, Centre for Molecular Medicine Norway (NCMM), University of Oslo, Forskningsparken, Gaustadalleén 21, 0349 Oslo, Norway.
Mohammed NourInstitut des Sciences Exactes et Appliquées (ISEA)-EA 4243, France University of New Caledonia, 98851 Nouméa, New Caledonia, France.
Laurence MarcourtSchool of Pharmaceutical Sciences, University of Geneva, CMU, Rue Michel Servet 1, 1211 Geneva, Switzerland.ORCID 0000-0002-9614-1099
Jean-Luc WolfenderSchool of Pharmaceutical Sciences, University of Geneva, CMU, Rue Michel Servet 1, 1211 Geneva, Switzerland.ORCID 0000-0002-0125-952X
Krystyna Skalicka-WoźniakDepartment of Natural Products Chemistry, Medical University of Lublin, 20-093 Lublin, Poland.ORCID 0000-0002-9313-5929
Medical University of Lublin · PLUniversity of Oslo · NOUniversity of Geneva · CHGrigore T. Popa University of Medicine and Pharmacy · ROUniversity of New Caledonia · NCUniversity of Warmia and Mazury in Olsztyn · PL

Funding

Medical Univeristy of Lublin GW/PB/59/2021
6 · The paper itself

Abstract

Epilepsy is a neurological disease that burdens over 50 million people worldwide. Despite the considerable number of available antiseizure medications, it is estimated that around 30% of patients still do not respond to available treatment. Herbal medicines represent a promising source of new antiseizure drugs. This study aimed to identify new drug lead candidates with antiseizure activity from endemic plants of New Caledonia. The crude methanolic leaf extract of

Indexed as

EpilepsyPentylenetetrazoleAnimalsAnticonvulsantsDisease Models, AnimalSeizuresZebrafishAnticonvulsantsPentylenetetrazolecoumarinselectrophysiologyepilepsyLFPliquid-liquid chromatographyrutaceaezebrafish

Identifiers

PMID36768918
PMCPMC9916433
OpenAlexW4318478515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.