Evidence map›Paper›PMID 36768892›Full record

ArticleInternational journal of molecular sciences2023

Zein Nanoparticles Containing Arginine-Based Surfactants: Physicochemical Characterization and Effect on the Biological Properties.

Lourdes Pérez, Adrià Sentís, Zakaria Hafidi, Aurora Pinazo, Maria Teresa García, Manuel Martín-Pastor, Francisco Fábio Oliveira de Sousa

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lourdes PérezDepartment of Surfactants and Nanobiotechnology, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), 08034 Barcelona, Spain.ORCID 0000-0002-3696-021X
Adrià SentísWhile was at Biocompatible Surfactant and Liquid Ionic Group, Institut de Química Avançada de Catalunya-CSIC, 08034 Barcelona, Spain.
Zakaria HafidiDepartment of Surfactants and Nanobiotechnology, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), 08034 Barcelona, Spain.ORCID 0000-0001-8554-5189
Aurora PinazoDepartment of Surfactants and Nanobiotechnology, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), 08034 Barcelona, Spain.
Maria Teresa GarcíaDepartment of Surfactants and Nanobiotechnology, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), 08034 Barcelona, Spain.ORCID 0000-0001-9967-3472
Manuel Martín-PastorUnidad de Resonancia Magnética, Área de Infraestructuras de Investigación, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain.ORCID 0000-0001-6024-1656
Francisco Fábio Oliveira de SousaDepartment of Surfactants and Nanobiotechnology, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), 08034 Barcelona, Spain.ORCID 0000-0002-7366-1622

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior PROCAD - AmazonEuropean Regional Development Fund (FEDER) 001Fundação de Amparo à Pesquisa do Estado do Amapá (FAPEAP) PRONEM 95/2018Ministry of Economy, Industry and Competitiveness CTQ2017-88948-PNational Council for Scientific and Technological Development PRONEM 95/2018
6 · The paper itself

Abstract

Cationic surfactants carry antimicrobial activity, based on their interaction and disruption of cell membranes. Nonetheless, their intrinsic toxicity limits their applicability. To overcome this issue, a feasible strategy consists of using solid nanoparticles to improve their delivery. The zein nanoparticles were loaded with four cationic arginine-based surfactants: one single chain Nα-lauroyl-arginine (LAM) and three Gemini surfactants Nα Nω-Bis (Nα-lauroyl-arginine) α, ω-diamide) (C

Indexed as

Anti-Infective AgentsNanoparticlesZeinArginineBacteriaMolecular Docking SimulationSurface-Active AgentsAnti-Infective AgentsArginineSurface-Active AgentsZeinamino acid surfactantsantimicrobialdockinghemolyticinteractionmonolayernanoparticlesnuclear magnetic ressonancezein

Identifiers

PMID36768892
PMCPMC9917094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.