Evidence map›Paper›PMID 36768861›Full record

SynthesisInternational journal of molecular sciences2023

Taste and Smell Disorders in Cancer Treatment: Results from an Integrative Rapid Systematic Review.

Tania Buttiron Webber, Irene Maria Briata, Andrea DeCensi, Isabella Cevasco, Laura Paleari

2 registry-linked trialsOpen access · goldAbstract readSystematic Review
In one paragraph

Synthesis in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
8.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06669416 narecruitingnot on this mapstarted 2024, after this paper: background citation

Effects of Patient Education and Self-Management in Cancer Patients Who Experience Chemotherapy-Induced Taste Alterations

TypeinterventionalSponsorWake Forest University Health SciencesRan2024 to 2026Enrolled400ConditionsChemotherapy Side Effects, Taste, AlteredArmsTaste Alteration Self-Assessment, Taste Alternation Self-Management
NCT07317752 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Incidenza Della Disgeusia Nei Pazienti Affetti da Carcinoma Mammario in Trattamento Chemioterapico: Uno Studio Pilota Prospettico

TypeobservationalSponsorAzienda Sanitaria Locale CN2 Alba-BraRan2026 to 2027Enrolled40ConditionsTaste Disorders, Breast Cancer, Quality of Life, Taste PerceptionArmsTaste Assessment / Nutritional Assessment / Quality of Life Assessment
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Eating Experiences of Patients With Cancer in the Hospital - A Qualitative Study.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The impact of taste and smell alterations on nutritional status and quality of life in individuals undergoing chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  12. Peer-led plant-based cooking workshops for post-cancer patients: an observational pilot study on dietary practices.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Observational
  13. Observational
  14. Taste alterations in patients with cancer: an overview and recommendations for future research.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Developing and regenerating a sense of taste.Current topics in developmental biology · 2025
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Tania Buttiron WebberDivision of Medical Oncology, E.O. Galliera Hospital, 16128 Genoa, Italy.ORCID 0000-0002-3605-2828
Irene Maria BriataDivision of Medical Oncology, E.O. Galliera Hospital, 16128 Genoa, Italy.ORCID 0000-0003-0767-0026
Andrea DeCensiDivision of Medical Oncology, E.O. Galliera Hospital, 16128 Genoa, Italy.ORCID 0000-0003-2635-4491
Isabella CevascoDepartment of Health Professions, E.O. Galliera Hospital, 16128 Genoa, Italy.
Laura PaleariResearch, Innovation and HTA Unit, (A.Li.Sa.) Liguria Health Authority, 16121 Genoa, Italy.ORCID 0000-0002-6176-2979
Ente Ospedaliero Ospedali Galliera · ITAgenzia Regionale per la Protezione dell'ambiente ligure · ITQueen Mary University of London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Taste and smell disorders (TSDs) are common side effects in patients undergoing cancer treatments. Knowing which treatments specifically cause them is crucial to improve patients' quality of life. This review looked at the oncological treatments that cause taste and smell alterations and their time of onset. We performed an integrative rapid review. The PubMed, PROSPERO, and Web of Science databases were searched in November 2022. The article screening and study selection were conducted independently by two reviewers. Data were analyzed narratively. Fourteen studies met the inclusion criteria and were included. A high heterogeneity was detected. Taste disorders ranged between 17 and 86%, while dysosmia ranged between 8 and 45%. Docetaxel, paclitaxel, nab-paclitaxel, capecitabine, cyclophosphamide, epirubicin, anthracyclines, and oral 5-FU analogues were found to be the drugs most frequently associated with TSDs. This review identifies the cancer treatments that mainly lead to taste and smell changes and provides evidence for wider studies, including those focusing on prevention. Further studies are warranted to make conclusive indication possible.

Indexed as

NeoplasmsOlfaction DisordersHumansQuality of LifeSmellTasteTaste Disorderscancer treatmentdysgeusiadysosmiarapid reviewsmelltaste

Identifiers

PMID36768861
PMCPMC9916934
OpenAlexW4318476350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.