Evidence map›Paper›PMID 36768762›Full record

ArticleInternational journal of molecular sciences2023

Stress-Related Immune Response and Selenium Status in Autoimmune Thyroid Disease Patients.

Ieva Vaivode, Tatjana Zake, Ieva Strele, Sabine Upmale-Engela, Deniss Gogins, Gita Gersone, Andrejs Skesters, Maija Dambrova, Ilze Konrade

Registry-linked trialAbstract read
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06527859 (Correlation Between Different Doses of Levothyroxine Supplementation and Peripheral Blood Th17/Treg Balance in Pregnant Women With Normal-high TSH and Positive TPOAb in the First Half of Pregnancy), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06527859 terminatednot on this map

Correlation Between Different Doses of Levothyroxine Supplementation and Peripheral Blood Th17/Treg Balance in Pregnant Women With Normal-high TSH and Positive TPOAb in the First Half of Pregnancy

TypeobservationalSponsorThird Affiliated Hospital of Zhengzhou UniversityRan2022 to 2024Enrolled64ConditionsPregnancy Related, Thyroid Stimulating, Hormone, CArmsLevothyroxin
3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ieva VaivodeDepartment of Internal Diseases, Riga Stradins University, LV-1007 Riga, Latvia.ORCID 0000-0002-0286-7228
Tatjana ZakeDepartment of Internal Diseases, Riga Stradins University, LV-1007 Riga, Latvia.
Ieva StreleInstitute of Occupational Safety and Environmental Health, Riga Stradins University, LV-1007 Riga, Latvia.ORCID 0000-0001-7880-2087
Sabine Upmale-EngelaDepartment of Internal Diseases, Riga Stradins University, LV-1007 Riga, Latvia.
Deniss GoginsDepartment of Internal Diseases, Riga Stradins University, LV-1007 Riga, Latvia.ORCID 0000-0001-6373-5985
Gita GersoneDepartment of Human Physiology and Biochemistry, Riga Stradins University, LV-1007 Riga, Latvia.
Andrejs SkestersInstitute of Occupational Safety and Environmental Health, Riga Stradins University, LV-1007 Riga, Latvia.ORCID 0000-0003-3726-8724
Maija DambrovaLatvian Institute of Organic Synthesis, LV-1006 Riga, Latvia.ORCID 0000-0002-1739-0928
Ilze KonradeDepartment of Internal Diseases, Riga Stradins University, LV-1007 Riga, Latvia.

Funding

Latvian Council of Science lzp-2018/2-0059
6 · The paper itself

Abstract

Autoimmune thyroid disease (AITD), including Graves' disease (GD) or Hashimoto's thyroiditis (HT), occurs due to genetic susceptibility and environmental factors, among which the role of stressful events remains controversial. This study investigated the relationship between the number and impact of stressful life events in AITD patients with selenium status, and the Th1/Th2/Th17 immune response. The study population included three groups: HT (

Indexed as

Graves DiseaseHashimoto DiseaseSeleniumCytokinesGenetic Predisposition to DiseaseHumansImmunityCytokinesSeleniumautoimmune thyroid diseasecytokinesglutathione peroxidasehuman healthselenoproteinsstress

Identifiers

PMID36768762
PMCPMC9917185

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.