Evidence map›Paper›PMID 36768612›Full record

ArticleInternational journal of molecular sciences2023

Crystal Structure of Inhibitor-Bound Bacterial Oligopeptidase B in the Closed State: Similarity and Difference between Protozoan and Bacterial Enzymes.

Dmitry E Petrenko, David M Karlinsky, Veronika D Gordeeva, Georgij P Arapidi, Elena V Britikova, Vladimir V Britikov, Alena Y Nikolaeva, Konstantin M Boyko, Vladimir I Timofeev, Inna P Kuranova and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Peptidases: Role and Function in Health and Disease.International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Dmitry E PetrenkoNational Research Center "Kurchatov Institute", 123182 Moscow, Russia.
David M KarlinskyShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0001-7100-6432
Veronika D GordeevaFederal Research and Clinical Center of Physical-Chemical Medicine of Federal Medical Biological Agency, 119435 Moscow, Russia.ORCID 0000-0001-8904-8235
Georgij P ArapidiShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0003-2323-1859
Elena V BritikovaInstitute of Bioorganic Chemistry of the National Academy of Sciences of Belarus, 220141 Minsk, Belarus.
Vladimir V BritikovInstitute of Bioorganic Chemistry of the National Academy of Sciences of Belarus, 220141 Minsk, Belarus.ORCID 0000-0002-1330-9539
Alena Y NikolaevaNational Research Center "Kurchatov Institute", 123182 Moscow, Russia.
Konstantin M BoykoA.N. Bach Institute of Biochemistry, Federal Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, Russia.ORCID 0000-0001-8229-189X
Vladimir I TimofeevShubnikov Institute of Crystallography, Federal Scientific Research Centre "Crystallography and Photonics" of the Russian Academy of Sciences, 119333 Moscow, Russia.
Inna P KuranovaShubnikov Institute of Crystallography, Federal Scientific Research Centre "Crystallography and Photonics" of the Russian Academy of Sciences, 119333 Moscow, Russia.
Anna G MikhailovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.
Eduard V BocharovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-3635-1609
Tatiana V RakitinaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-3096-8659

Funding

Russian Science Foundation 21-74-20154
6 · The paper itself

Abstract

The crystal structure of bacterial oligopeptidase B from

Indexed as

Serine EndopeptidasesTrypanosoma brucei bruceiCatalysisoligopeptidase BSerine EndopeptidasesAlphaFoldbioinformaticscatalytic triadchloromethyl ketone inhibitorconformational transitionsoligopeptidase Bprolyl oligopeptidaseserine protease

Identifiers

PMID36768612
PMCPMC9917282

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.